Peripheral blood is a source of BCR-ABL-negative pre-progenitors in early chronic phase chronic myeloid leukemia
… blood at diagnosis. Apheresis product collected at diagnosis is a more abundant source
of BCRABL-… Thus, apheresis product could potentially be utilized as a source of BCR-ABL-nega- …
of BCRABL-… Thus, apheresis product could potentially be utilized as a source of BCR-ABL-nega- …
Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients.
SK Chai, GL Nichols, P Rothman - Journal of immunology …, 1997 - journals.aai.org
… find constitutive STAT activation in BCRAbl-expressing cell lines… peripheral blood cells of
patients with BCR-Abl-expressing leukemias. These studies suggest that the expression of BCR…
patients with BCR-Abl-expressing leukemias. These studies suggest that the expression of BCR…
Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia
… To investigate the mechanisms behind the leukemic expansion of BCR/ABL-positive …
from peripheral blood (PB) and bone marrow (BM) of 37 patients with newly diagnosed BCR/ABL-…
from peripheral blood (PB) and bone marrow (BM) of 37 patients with newly diagnosed BCR/ABL-…
Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define …
… persisting low levels of BCR-ABL transcripts but never … BCR-ABL transcript levels after
allograft is variable; only a minority of patients with fluctuating or persistent low levels of BCR-ABL …
allograft is variable; only a minority of patients with fluctuating or persistent low levels of BCR-ABL …
Serial monitoring of BCR–ABL by peripheral blood real‐time polymerase chain reaction predicts the marrow cytogenetic response to imatinib mesylate in chronic …
L Wang, K Pearson, L Pillitteri… - British journal of …, 2002 - Wiley Online Library
… BCR–ABL expression is relatively high, although having little effect on the ratio obtained from
samples with low BCR–ABL … that the serial peripheral blood BCR–ABL/ABL ratio may be …
samples with low BCR–ABL … that the serial peripheral blood BCR–ABL/ABL ratio may be …
BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy
JQ Guo, JY Lian, YM Xian, MS Lee, AB Deisseroth… - 1994 - ashpublications.org
… ABL band. Our results show that we can detect the BCR-ABL protein both in peripheral blood
… Also, our Western blot assay not only detected P210 BCR-ABL in Ph'-positive CML patients…
… Also, our Western blot assay not only detected P210 BCR-ABL in Ph'-positive CML patients…
STI571: targeting BCR-ABL as therapy for CML
MJ Mauro, BJ Druker - The oncologist, 2001 - academic.oup.com
… trial, 91% of patients showed a hematological response; 63% of patients achieved a
complete hematological response but not all patients had recovery of peripheral blood counts. …
complete hematological response but not all patients had recovery of peripheral blood counts. …
An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR
MC Müller, G Saglio, F Lin, H Pfeifer, RD Press… - …, 2007 - haematologica.org
… BCR-ABL, total ABL, and G6PD transcript concentrations and to calculate the BCR-ABL/total
ABL and BCR-ABL/… calculated using TaqMan PCR for BCR-ABL, total ABL, and G6PD of …
ABL and BCR-ABL/… calculated using TaqMan PCR for BCR-ABL, total ABL, and G6PD of …
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
BJ Druker, S Tamura, E Buchdunger, S Ohno… - Nature medicine, 1996 - nature.com
… Cellular proliferation and tumor formation by Bcr-Abl-expressing cells … peripheral blood
or bone marrow from patients with CML, there was a 92–98% decrease in the number of bcr-abl …
or bone marrow from patients with CML, there was a 92–98% decrease in the number of bcr-abl …
Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.
MA Kelliher, J McLaughlin, ON Witte… - Proceedings of the …, 1990 - National Acad Sciences
… of BCR/ABL was present in the peripheral blood samples. … , unique fragment for each
BCR/ABL provirus revealed the … in the peripheral blood is a consequence of BCR/ABL infection …
BCR/ABL provirus revealed the … in the peripheral blood is a consequence of BCR/ABL infection …
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