Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions

V Micale, A Tamburella, GM Leggio, C Mazzola… - … and Behavior, 2008 - Elsevier
… The present study clearly shows that the selective tachykinin NK2 receptor antagonist,
saredutant given systemically to rodents is effective to improve the behavioral performance in …

Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice

RM Teixeira, ARS Santos, SJ Ribeiro, JB Calixto… - European journal of …, 1996 - Elsevier
… the effects of intracerebroventricular administration of selective agonists and antagonists for
tachykinin NK 1 and NK 2 receptors … of both tachykinin NK 1 and NK 2 receptor antagonists

Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress

J Culman, S Klee, C Ohlendorf, T Unger - Journal of Pharmacology and …, 1997 - ASPET
… With the help of these newly developed tachykinin receptor antagonists, we can now show
for the … an integrated cardiovascular and behavioral stress responses to a noxious stimulus. …

Cardiovascular and behavioural effects of intracerebroventricularly administered tachykinin NK3 receptor antagonists in the conscious rat

E Cellier, L Barbot, D Regoli… - British journal of …, 1997 - Wiley Online Library
receptors (Regoli et al., 1994b). Indeed, R820 did not block the central cardiovascular and
behavioural effects induced by the NK 1 receptor … of central NK 2 receptors (Picard & Couture, …

Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea‐pig

O Piot, J Betschart, I Grall, S Ravard… - British journal of …, 1995 - Wiley Online Library
receptors, the purpose of the present study was to determine the behavioural profile of a
number of tachykinin … Anxiolyticactivity of tachykinin NK2 receptor antagonists in themouse light-…

Tachykinin NK2 receptor antagonists for the treatment of irritable bowel syndrome

A Lecci, A Capriati, CA Maggi - British journal of pharmacology, 2004 - Wiley Online Library
Tachykinin NK2 receptors are expressed in the … Experimental data indicate a role for these
receptors in the … It is concluded that blockade of peripheral tachykinin NK2 receptors should …

Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat.

C Tschöpe, P Picard, J Culmann, A Prat… - British journal of …, 1992 - ncbi.nlm.nih.gov
… selective NK2b receptor antagonist, R … behavioural effects of NKA were not affected by
(±)-CP 96,345 which suggests a specific action on NKI receptors although non-tachykinin receptor

Biochemical and pharmacological activities of SR 144190, a new potent non-peptide tachykinin NK2 receptor antagonist

X Emonds-Alt, C Advenier, C Cognon, T Croci, S Daoul… - Neuropeptides, 1997 - Elsevier
… A binding to NK 2 receptors from various species, including … and competitive antagonist of
NK2 receptors with apparent … and behavioural effects of centrally administered tachykinins

Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists

P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
… , to confirm the participation of NKI and NK2 receptors in central cardiovascular and behavioural
NK2 receptors since only the NK2 receptor antagonist SR 48968 reduced the biological …

Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B

J Culman, B Wiegand, H Spitznagel… - British journal of …, 1995 - Wiley Online Library
… at central tachykinin receptors in vivo we investigated the effects of … antagonists to dissociate
the central cardiovascular and behavioural effects of tachykinins on NK, and NK2 receptor