Background Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen
that damages DNA by forming adducts. This damage along with activation of the aryl …

… MCF-7 cells with increasing P-gp expression we examined this hypothesis using benzo(a)pyrene, …
-resistant to benzo(a)pyrene and the rates of efflux for benzo(a)pyrene were higher in …

… Benzo[a]pyrene (BaP) is one of the major classes of … family with BaP in human breast cancer
MCF-7 cells. The effects of … When MCF-7 cells were incubated with 2μM BaP for 24h, three …

… (FL) and benzo[a]pyrene (BaP) on human breast cancer cell line (MCF–7 cells) to determine
… /ml and 500 ng/ml) decreased MCF–7 cell viability significantly as demonstrated by the MTT …

… monitor the activity of 18,224 cDNA clones in MCF-7 and HepG2 cells exposed to the
carcinogen benzo(a)pyrene (BaP) or its non-carcinogenic isomer benzo(e)pyrene (BeP). Time and …

Pro-carcinogens, such as benzo[a]pyrene (B[a]P), that are exogenous ligands of the aromatic
hydrocarbon receptor may influence the susceptibility of target-cell populations through the …

… MCF-7 human breast cancer cells were cultured for 3 months in 1 microM benzo[a]pyrene
(BaP), and resistant clones were screened for inducibility of CYP1A1 gene expression by 2,3,7…

… inhibiting ABC-transporters affect the toxicity of benzo(a)pyrene (BP). MCF-7 breast
adenocarcinoma cells were cultured for 24 and 48 h with benzo(a)pyrene (1 μM) and the transporter …

Benzo(a)pyrene (BaP) is a representative polycyclic aromatic hydrocarbon (PAH) compound,
which has been implicated in cancer initiation and promotion. Although BaP is one of the …

… Using a GeneMAP™ CancerArray, we analyzed in breast cancer MCF‐7 cells the temporal
effects of the AhR agonist benzo[a]pyrene (B[a]P), which is a prototype PAH and known …