Midlife blood pressure, plasma β-amyloid, and the risk for Alzheimer disease: the Honolulu Asia Aging Study

NS Shah, JS Vidal, K Masaki, H Petrovitch… - …, 2012 - Am Heart Assoc
β-Amyloid (Aβ), a vasoactive protein, and elevated blood pressure (BP) levels are associated
with Alzheimer disease (AD) and possibly vascular dementia. We investigated the joint …

Blood amyloid beta levels in healthy, mild cognitive impairment and Alzheimer's disease individuals: replication of diastolic blood pressure correlations and analysis of …

A Ruiz, P Pesini, A Espinosa, V Pérez-Grijalba… - PLoS …, 2013 - journals.plos.org
… We confirmed that diastolic blood pressure (DBP) is consistently correlated with blood DA
Aβ40 levels (r=-0.19, P=0.032). These results were consistent in the three phenotypic groups …

Intravascular β-amyloid infusion increases blood pressure: implications for a vasoactive role of β-amyloid in the pathogenesis of Alzheimer's disease

GW Arendash, GC Su, FC Crawford, KB Bjugstad… - Neuroscience …, 1999 - Elsevier
… resulting in an acute rise in blood pressure (BP) in vivo. … /kg, ip), and a digital blood pressure
analyzer (Micro–Med, KY) … mean arterial blood pressure (MAP), systolic/diastolic pressures, …

Midlife blood pressure, amyloid-β, and risk for Alzheimer disease: one more reason to treat hypertension

MF Elias, A Davey - Hypertension, 2012 - Am Heart Assoc
… Using a prospective design, these investigators examined the association between midlife
blood pressure (BP) and amyloid-β (Aβ) peptide levels and risk for late-life AD and VaD in …

The relationship between blood lipids and plasma amyloid beta is depend on blood pressure: a population-based cross-sectional study

N Hu, L Gao, Y Jiang, S Wei, S Shang, C Chen… - Lipids in Health and …, 2020 - Springer
… lipids and plasma Aβ, we divided the total population into high blood pressure and normal
blood pressure according to the standard of SBP greater than or equal to 140 mmHg and/or …

Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

T Kim, D Yi, MS Byun, H Ahn, JH Jung, N Kong… - Alzheimer's research & …, 2022 - Springer
… In our study, we examined the relationships of a history of hypertension and high current
blood pressure (BP) with in vivo AD pathologies including β-amyloid (Aβ) and tau and also …

Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons

JBS Langbaum, K Chen, LJ Launer, AS Fleisher… - Neurobiology of …, 2012 - Elsevier
… collecting information on history of hypertension and use of blood pressure lowering
medications, using clinical ratings, neuropsychological tests, … Measurement of blood pressure

Association of low systolic blood pressure with postmortem amyloid-β and tau

S Oveisgharan, AW Capuano, A Kapasi… - Journal of …, 2020 - content.iospress.com
… Finally, we replaced SBP by diastolic blood pressure (DBP) to examine if the modification
of the association between Aβ and tau by SBP was also seen by DBP. Analyses controlled for …

Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT)

NM Pajewski, FM Elahi, MK Tamura… - Alzheimer's & …, 2022 - Wiley Online Library
blood pressure (BP) … blood pressure < 120 mm Hg), compared to less aggressive treatment
(< 140 mm Hg), is not associated with changes in plasma biomarkers of plasma amyloid beta

Blood pressure and the risk for dementia—A double edged sword

SP Kennelly, BA Lawlor, RA Kenny - Ageing research reviews, 2009 - Elsevier
… state may lead to increased cerebral β-amyloid accumulation. … ) blood pressure separately.
We will then explore some of the possible mechanisms by which changes in blood pressure