Heart rate and rhythm and the benefit of beta-blockers in patients with heart failure

…, Beta-Blockers in Heart Failure Collaborative … - Journal of the American …, 2017 - jacc.org
… This analysis explored the prognostic importance of heart rate in patients with heart failure
with reduced ejection fraction in randomized controlled trials comparing beta-blockers and …

Does tight heart rate control improve beta-blocker efficacy? An updated analysis of the noncardiac surgical randomized trials

WS Beattie, DN Wijeysundera, K Karkouti… - Anesthesia & …, 2008 - journals.lww.com
… the most effective control of heart rate are associated with a … , suggesting that effective
control of heart rate is important for … of β-blockers does not reliably decrease heart rates, and …

Beta blockers and chronic heart failure patients: prognostic impact of a dose targeted beta blocker therapy vs. heart rate targeted strategy

A Corletto, H Fröhlich, T Täger, M Hochadel… - Clinical Research in …, 2018 - Springer
… In the present study, we found that mortality was highest in patients without beta blocker
treatment irrespective of underlying HR. Our data, therefore, support the use of beta blockers in …

Relation of beta-blocker–induced heart rate lowering and cardioprotection in hypertension

S Bangalore, S Sawhney, FH Messerli - Journal of the American College of …, 2008 - jacc.org
… To the contrary, the results of the present analyses show that reduction of heart rate with
beta-blocker therapy is associated with increased risk of cardiovascular events. …

Meta-analysis: β-blocker dose, heart rate reduction, and death in patients with heart failure

FA McAlister, N Wiebe, JA Ezekowitz… - Annals of Internal …, 2009 - acpjournals.org
… the narrow range of heart rate reduction values in the included trials limit our ability to
speculate about the “optimal” magnitude of heart rate reduction to aim for with β-blocker therapy. …

Heart rate achieved or betablocker dose in patients with chronic heart failure: which is the better target?

D Cullington, KM Goode, AL Clark… - … journal of heart failure, 2012 - Wiley Online Library
… suggest that treatment to reduce resting heart rate in patients with heart failure to <65 bpm
is associated with a better prognosis. However, risk must increase with very low heart rates. …

Heart rate and cardiovascular disease: an alternative to beta blockers

M Liang, A Puri, G Devlin - Cardiology research and practice, 2009 - Wiley Online Library
… of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in
therapeutic heart rate management especially in patients who are intolerant of beta-blockers. …

Heart rate, beta-blocker use, and outcomes of heart failure with reduced ejection fraction

NE Ibrahim, HK Gaggin, A Turchin… - … –Cardiovascular …, 2019 - academic.oup.com
… least 50% guideline-directed medical therapy beta-blocker dose and heart rate ≥70 vs. <70 …
heart rate despite being on at least 50% guideline-directed medical therapy beta-blocker

Effects of cardiac rehabilitation and beta-blocker therapy on heart rate variability after first acute myocardial infarction

G Malfatto, M Facchini, L Sala, G Branzi… - The American journal of …, 1998 - Elsevier
… AMI shifts cardiovascular autonomic control of heart rate in a … β blockers on HRV and are
additive and not redundant. Thus, it is reasonable to suggest the combination β-blocker therapy

Individualizing beta-adrenergic blocker therapy: patient-specific target-based heart rate control

KJ Tuman, RJ McCarthy - Anesthesia & Analgesia, 1999 - journals.lww.com
… -controlled trial evaluating the antiischemic efficacy of specifically tailored beta-blocker
therapy to control individual patient heart rateheart rate at which preoperative Holter monitor