Oxidative and nitrosative stress induces peroxiredoxins in pancreatic beta cells
A Bast, G Wolf, I Oberbäumer, R Walther - Diabetologia, 2002 - Springer
… present in pancreatic beta cells and if they are inducible by oxidative and nitrosative stress.
Methods. To detect these enzymes in insulin-producing beta cells we used semiquantitative …
Methods. To detect these enzymes in insulin-producing beta cells we used semiquantitative …
Oxidative and nitrosative stress in β-cell apoptosis: their contribution to β-cell lossin type 1 diabetes mellitus
D Watson, AC Loweth - British journal of biomedical science, 2009 - Taylor & Francis
… of the current opinions relating to β-cell apoptosis in type 1 DM, … and nitrosative stress. It will
consider evidence from clonal … Role of pancreatic beta cells in the process of beta cell death…
consider evidence from clonal … Role of pancreatic beta cells in the process of beta cell death…
Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice
Y Yagishita, T Fukutomi, A Sugawara, H Kawamura… - Diabetes, 2014 - Am Diabetes Assoc
… oxidative stress response and metabolism. However, the roles Nrf2 plays in prevention of
pancreatic β-cell damage remain elusive. To demonstrate the roles of Nrf2 in pancreatic β-cells…
pancreatic β-cell damage remain elusive. To demonstrate the roles of Nrf2 in pancreatic β-cells…
Carnosine protects pancreatic beta cells and islets against oxidative stress damage
… beta cells, we tested both L-carnosine isomer (L-CA) and D-carnosine isomer (D-CA) on
stressed insulin-producing cells, using two different cell … improve pancreatic beta cell viability …
stressed insulin-producing cells, using two different cell … improve pancreatic beta cell viability …
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
C Szabo - British journal of pharmacology, 2009 - Wiley Online Library
… Here we overview the role of reactive nitrogen species (nitrosative stress) and associated
pathways in the pathogenesis of diabetic vascular complications. Increased extracellular …
pathways in the pathogenesis of diabetic vascular complications. Increased extracellular …
Upregulation of phagocyte-like NADPH oxidase by cytokines in pancreatic beta-cells: attenuation of oxidative and nitrosative stress by 2-bromopalmitate
AM Mohammed, K Syeda, T Hadden… - Biochemical …, 2013 - Elsevier
… of palmitoylation as a unifying mechanism involved in the induction of Nox2-mediated
oxidative stress and iNOS-mediated nitrosative stress in pancreatic β-cells (see Section 4). …
oxidative stress and iNOS-mediated nitrosative stress in pancreatic β-cells (see Section 4). …
Oxidative/nitrosative stresses trigger type I diabetes: preventable in streptozotocin rats and detectable in human disease
K Van Dyke, N Jabbour, R Hoeldtke… - Annals of the New …, 2010 - Wiley Online Library
… This apparently occurs because the nitric oxide (NO) (from STZ) generated in the beta
cells is oxidized to nitrite by c-PTIO preventing diabetes. STZ generates NO producing a NO-…
cells is oxidized to nitrite by c-PTIO preventing diabetes. STZ generates NO producing a NO-…
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies
… The pathogenetic role of nitrosative stress and peroxynitrite, … This review focuses on
the role of nitrosative stress and … Increased nitrotyrosine formation in pancreatic islet betacells…
the role of nitrosative stress and … Increased nitrotyrosine formation in pancreatic islet betacells…
… deficiency triggers an oxidative-nitrosative stress-mediated apoptotic cell death and impedes insulin biosynthesis in RINm5F pancreatic islet β–cells: Relevant to the …
HC Hsu, JF Chiou, YH Wang, CH Chen, SY Mau… - PLoS …, 2013 - journals.plos.org
… FD Triggered Intracellular GSH Depletion in RINm5F Cells We hypothesized that FD-induced
oxidative-nitrosative stress could trigger intracellular GSH depletion. To test this possibility, …
oxidative-nitrosative stress could trigger intracellular GSH depletion. To test this possibility, …
Contribution of oxidative stress and impaired biogenesis of pancreatic β-cells to type 2 diabetes
P Ježek, M Jabůrek, L Plecitá-Hlavatá - Antioxidants & Redox …, 2019 - liebertpub.com
… Human bcells were suggested to be less prone to oxidative stress than rodent … , causes a
mild oxidative and nitrosative stress accompanied by transiently diminished respiration. NO can …
mild oxidative and nitrosative stress accompanied by transiently diminished respiration. NO can …