Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance
W Xie, W Hu, Z Huang, M Li, H Zhang, X Huang… - Burns & …, 2022 - academic.oup.com
… beneficial effect of betulinic acid (BA) on diabetic wound healing. … Betulinic acid ameliorates
hyperglycemia-mediated glucose transporter type 4 suppression and glucose intolerance …
hyperglycemia-mediated glucose transporter type 4 suppression and glucose intolerance …
Beneficial effect of betulinic acid on hyperglycemia via suppression of hepatic glucose production
SJ Kim, HY Quan, KJ Jeong, DY Kim… - Journal of agricultural …, 2014 - ACS Publications
… effect of betulinic acid (BA) on hepatic glucose production was examined in HepG2 cells
and high fat diet (HFD)-fed ICR mice. BA significantly inhibited the hepatic glucose production (…
and high fat diet (HFD)-fed ICR mice. BA significantly inhibited the hepatic glucose production (…
Betulinic acid improves insulin sensitivity, hyperglycemia, inflammation and oxidative stress in metabolic syndrome rats via PI3K/Akt pathways
RA Ajala-Lawal, NO Aliyu… - Archives of physiology and …, 2020 - Taylor & Francis
… Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced
obesity mice. Scandinavian journal of clinical and laboratory investigation, 73 (8), 607–614. …
obesity mice. Scandinavian journal of clinical and laboratory investigation, 73 (8), 607–614. …
Antidiabetic effects of betulinic acid mediated by the activation of the AMP-activated protein kinase pathway
TJ Song, CH Park, KR In, JB Kim, JH Kim, M Kim… - PLoS …, 2021 - journals.plos.org
… of the naturally occurring compound betulinic acid (BA), a … glucose tolerance in BA-treated
ICR mice To investigate the effect of BA on glucose tolerance, we measured blood glucose …
ICR mice To investigate the effect of BA on glucose tolerance, we measured blood glucose …
Betulinic acid ameliorates postprandial hyperglycemia in diabetic mice
JK Lee, HA Lee, JS Han - 생명과학회지, 2022 - dbpia.co.kr
… The objective of this study was to investigate whether betulinic acid … Our results revealed
that betulinic acid has potent inhibitory … Our results showed that betulinic acid may be a potent …
that betulinic acid has potent inhibitory … Our results showed that betulinic acid may be a potent …
Binding interaction of betulinic acid to α-glucosidase and its alleviation on postprandial hyperglycemia
S Chen, B Lin, J Gu, T Yong, X Gao, Y Xie, C Xiao… - Molecules, 2022 - mdpi.com
… In the present study, we reported the binding interaction of betulinic acid (BA), a … glucose
tolerance test (OGTT), which was performed as the ODTT modus. The oral dose of glucose …
tolerance test (OGTT), which was performed as the ODTT modus. The oral dose of glucose …
New pharmacological opportunities for betulinic acid
JL Ríos, S Máñez - Planta medica, 2018 - thieme-connect.com
… way, betulinic acid stimulates glucose uptake and glycogen synthesis through the AMPK-
GSK-3β pathway. In fact, betulinic acid (… of phosphoenolpyruvate carboxykinase and glucose-6-…
GSK-3β pathway. In fact, betulinic acid (… of phosphoenolpyruvate carboxykinase and glucose-6-…
Oleanolic, ursolic, and betulinic acids as food supplements or pharmaceutical agents for type 2 diabetes: promise or illusion?
FSG Silva, PJ Oliveira, MF Duarte - Journal of agricultural and …, 2016 - ACS Publications
… Several studies demonstrated the improvement of glucose tolerance being often accompanied
by alterations in the lipid profile, by decreasing total cholesterol, triglycerides (TG), and …
by alterations in the lipid profile, by decreasing total cholesterol, triglycerides (TG), and …
Betulinic acid and 1, 25 (OH) 2 vitamin D3 share intracellular signal transduction in glucose homeostasis in soleus muscle
… Immediately, rats received the treatment (vehicle or BA) and after 30 min they were overloaded
with glucose. The glucose tolerance curve was initiated just after the glucose overload …
with glucose. The glucose tolerance curve was initiated just after the glucose overload …
A 70% Ethanol Extract of Mistletoe Rich in Betulin, Betulinic Acid, and Oleanolic Acid Potentiated β‐Cell Function and Mass and Enhanced Hepatic Insulin Sensitivity
BS Ko, S Kang, BR Moon, JA Ryuk… - … and Alternative Medicine, 2016 - Wiley Online Library
… among the major terpenoids (betulin, betulinic acid, and oleanolic acid) in the extracts were
… serum glucose concentrations during the oral glucose tolerance test. Oral glucose tolerance …
… serum glucose concentrations during the oral glucose tolerance test. Oral glucose tolerance …
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