Cluster randomised trials with a binary outcome and a small number of clusters: comparison of individual and cluster level analysis method

JA Thompson, C Leyrat, KL Fielding… - BMC Medical Research …, 2022 - Springer
Conclusion We recommend that CRTs with ≤ 30 clusters and a binary outcome use an …
or restricted pseudolikelihood GLMM both with DoF clusters minus cluster-level parameters. …

… number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study

D Barker, C D'Este, MJ Campbell, P McElduff - Trials, 2017 - Springer
… In summary we recommend that SW-CRTs with a limited number of clusters and binary
outcomes should be analysed using a GLMM. Our strongest recommendation of all is that a cross-…

Analysis of binary outcomes from randomised trials including multiple births: when should clustering be taken into account?

LN Yelland, AB Salter, P Ryan… - Paediatric and perinatal …, 2011 - Wiley Online Library
… , and make recommendations regarding if and when clustering should be taken into … on
binary outcomes, such as mortality and morbidity, we also restrict our attention to such outcomes, …

A comparison of the statistical power of different methods for the analysis of cluster randomization trials with binary outcomes

PC Austin - Statistics in Medicine, 2007 - Wiley Online Library
… We let Yijl denote the binary outcomes for the lth subject in the ijth cluster and Yij denote the
total number of positive responses in the ijth cluster. ˆPij =… Number of Mean number clusters

A simple method for the analysis of clustered binary data

JNK Rao, AJ Scott - Biometrics, 1992 - JSTOR
… for the analysis of independent binary data after a small amount of preprocessing. The …
clustered binary data: testing homogeneity of proportions, estimating dose-response models and …

Measures of between‐cluster variability in cluster randomized trials with binary outcomes

A Thomson, R Hayes, S Cousens - Statistics in Medicine, 2009 - Wiley Online Library
… different assumptions regarding the between-cluster variability in the intervention arm of a …
for binary outcome data between two common measures of between-cluster variability: k, the …

Analysis of a cluster randomized trial with binary outcome data using a multi‐level model

RZ Omar, SG Thompson - Statistics in medicine, 2000 - Wiley Online Library
… Convergence can, however, be a problem for multi-level models with binary data. Also, if
there are many clusters with small number of units, thus having some clusters where all …

On small‐sample inference in group randomized trials with binary outcomes and cluster‐level covariates

PM Westgate - Biometrical journal, 2013 - Wiley Online Library
… the number of clusters is not large, and the sizes of these clusters are on a smaller scale than
outcomes are binary indicators of a desired outcome (success), while allowing for possible …

Choosing appropriate analysis methods for cluster randomised cross‐over trials with a binary outcome

KE Morgan, AB Forbes, RH Keogh… - Statistics in …, 2017 - Wiley Online Library
… most appropriate for binary outcomes from … binary outcome. We consider both models that
estimate a treatment odds ratio (OR), including hierarchical models and GEEs, and also cluster

Bayesian methods of analysis for cluster randomized trials with binary outcome data

RM Turner, RZ Omar, SG Thompson - Statistics in medicine, 2001 - Wiley Online Library
… The validity of this assumption is di cult to assess, particularly when the number of clusters
is small, as it is in many cluster randomized trials. A standard method of checking for normality …