[HTML][HTML] New multiplex PCR method for the detection of Clostridium difficile toxin A (tcdA) and toxin B (tcdB) and the binary toxin (cdtA/cdtB) genes applied to a Danish …
S Persson, M Torpdahl, KEP Olsen - Clinical microbiology and infection, 2008 - Elsevier
… Strains that were positive for the binary toxin were also subjected to PCR ribotyping in order
… strain of PCR ribotype 027. No strains in the present study matched the 027 PCR ribotype. …
… strain of PCR ribotype 027. No strains in the present study matched the 027 PCR ribotype. …
Characterization of clinical Clostridium difficile isolates by PCR ribotyping and detection of toxin genes in Austria, 2006–2007
A Indra, D Schmid, S Huhulescu… - Journal of medical …, 2008 - microbiologyresearch.org
… Binary toxin genes encoding binary toxin were found in 10/142 isolates (7.0 %): once for
ribotype 027, in three cases of ribotype … None of the ten binary toxin-positive cases in our study …
ribotype 027, in three cases of ribotype … None of the ten binary toxin-positive cases in our study …
Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile
S Stubbs, M Rupnik, M Gibert, J Brazier… - FEMS microbiology …, 2000 - academic.oup.com
… of binary toxin genes in C. difficile. The study also investigated variation in binary toxin genes
and … between the possession of binary toxin genes, changes in LCT genes and ribotype. …
and … between the possession of binary toxin genes, changes in LCT genes and ribotype. …
Simultaneous detection and ribotyping of Clostridioides difficile, and toxin gene detection directly on fecal samples
TM van Rossen, J van Prehn, A Koek, M Jonges… - … Resistance & Infection …, 2021 - Springer
… The presence of toxin genes specific for different ribotypes was … , toxin A, B and binary toxin
B genes were detected but not … presence of binary toxin B but not binary toxin A gene have …
B genes were detected but not … presence of binary toxin B but not binary toxin A gene have …
Prevalence and Characterization of a Binary Toxin (Actin-Specific ADP-Ribosyltransferase) from Clostridium difficile
C Gonçalves, D Decré, F Barbut… - Journal of clinical …, 2004 - Am Soc Microbiol
… We used those that were reported to have the most discriminatory power, such as PCR
ribotyping, AP-PCR, and PFGE (10). The results of the combined markers were consistent and …
ribotyping, AP-PCR, and PFGE (10). The results of the combined markers were consistent and …
Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance
DN Gerding, S Johnson, M Rupnik, K Aktories - Gut microbes, 2014 - Taylor & Francis
… that binary toxin genes were present in some PCR ribotypes … in different PCR ribotypes in
the large Cardiff PCR ribotype … had the genes for binary toxin, however, not all gene positive …
the large Cardiff PCR ribotype … had the genes for binary toxin, however, not all gene positive …
[HTML][HTML] Binary toxin and death after Clostridium difficile infection
S Bacci, K Mølbak, MK Kjeldsen… - Emerging infectious …, 2011 - ncbi.nlm.nih.gov
… genes for A, B, and binary toxin. The latter group comprised patients infected with strains of
PCR ribotype … Patients with binary toxin had higher case-fatality rates than patients without …
PCR ribotype … Patients with binary toxin had higher case-fatality rates than patients without …
Comparison of resistance against erythromycin and moxifloxacin, presence of binary toxin gene and PCR ribotypes in Clostridium difficile isolates from 1990 and …
C Ilchmann, NH Zaiss, A Speicher, M Christner… - European journal of …, 2010 - Springer
… belonging to PCR ribotype 027 [1]. This strain produces binary toxin CDT, encoded by cdtA
and cdtB, and has a partial deletion of the regulatory tcdC gene, resulting in toxin A and B …
and cdtB, and has a partial deletion of the regulatory tcdC gene, resulting in toxin A and B …
[HTML][HTML] Prevalence and pathogenicity of binary toxin–positive Clostridium difficile strains that do not produce toxins A and B
C Eckert, A Emirian, A Le Monnier, L Cathala… - New microbes and new …, 2015 - Elsevier
… a 39 bp deletion in the tcdC gene. Binary toxin genes were present, and the strain was
characterized as toxinotype XIb. This strain belonged to the same PCR ribotype (033/033-like) as …
characterized as toxinotype XIb. This strain belonged to the same PCR ribotype (033/033-like) as …
Lack of association of tcdC type and binary toxin status with disease severity and outcome in toxigenic Clostridium difficile
SD Goldenberg, GL French - Journal of infection, 2011 - Elsevier
… difficile, especially ribotype 027. We analysed the prevalence of binary toxin genes and tcdC
… The majority (83%) belonged to one of five tcdC types and 8% were ribotype 027. There …
… The majority (83%) belonged to one of five tcdC types and 8% were ribotype 027. There …
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