… of inflammatory signaling in macrophages by genome-wide expression screening for genes
which drove expression of the inflammatory … of key innate immune signaling molecules has …

… signaling partner, RIP2, is directly K63-polyubiquitinated by ITCH, an E3 ubiquitin ligase that
when lost genetically causes widespread inflammatory … We also show that NOD2 can bind …

… Furthermore, a large cohort of inflammatory response genes was found to bind NCoR and
… for appropriate regulation by inflammatory and anti-inflammatory signaling inputs. The full …

… signaling pathways, likely independent of its RNA-binding role. … of Sam68 in inflammatory
signaling and inflammatory diseases. … of the direct and indirect binding partners of Sam68 is …

… by ligands of either partner (Figure 1). LXR/RXR heterodimers bind to LXR-responsive …
Binding of ligand to LXR results in a conformational change that facilitates coactivator-for-…

… targeting inflammatory signaling pathways … signaling when it interacts with its other partner,
the transmembrane activator and CAML interactor (TACI). TACI signaling upon BAFF binding …

… (TRAF) proteins transduce signals from activated Toll-like receptor 4 in response to LPS, or
IL-1 and TNF cytokine receptors, to different intracellular signaling pathways, including those …

… peptide, which acts as an inflammatory mediator. It is a constituent … factor XII, an initiating
protein that binds to charged surface … such as trauma and inflammation, which binds to its kinin …

… inflammation and inflammatory signaling cascades. Following the initiation and propagation
of inflammatory signaling … state, TRAF3 acts as a binding partner for NIK bringing it close to …

… inflammatory cytokines and chemokines. Emerging data show that TNFSF ligand–receptor
signaling pathways are active in inflammatory … their ligand-binding extracellular regions and …