Diminished expression of transcription factors nuclear factor κB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting …

M Torroella-Kouri, X Ma, G Perry, M Ivanova, PJ Cejas… - Cancer research, 2005 - AACR
… macrophage cytotoxicity, low levels of nitric oxide expression, and decreased … binding
protein (C/EBP) expressions, as well as diminished nuclear translocation and DNA binding

Diminished Expression of Insulin-like Growth Factor (IGF) Binding Protein-5 and Activation of IGF-I-mediated Autocrine Growth in Simian Virus 40-transformed Human …

JG Reeve, A Guadaño, J Xiong, J Morgan… - Journal of Biological …, 1995 - ASBMB
… We show that IGFBP-5 gene expression and the expression of membrane-associated
and secreted IGFBP-5 is markedly diminished in SV 40-transformed fibroblasts and present …

Diminished prevalence but preserved synaptic distribution of N-methyl-D-aspartate receptor subunits in the methyl CpG binding protein 2 (MeCP2)-null mouse brain

E Maliszewska-Cyna, D Bawa, JH Eubanks - Neuroscience, 2010 - Elsevier
… The overall prevalence of the GluN1 and GluN2A subunits is diminished in MeCP2-null …
The decreases did not occur in any specific microdomain, as expression in each was diminished

CREB-binding protein sequestration by expanded polyglutamine

A McCampbell, JP Taylor, AA Taye… - Human molecular …, 2000 - academic.oup.com
… We present evidence that soluble levels of CBP are reduced in cells expressing expanded
… to trophic factors essential for survival is diminished. Our data showing a decrease in soluble …

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

JS Steffan, A Kazantsev… - Proceedings of the …, 2000 - National Acad Sciences
… the proline-rich region, shows greatly diminished binding, suggesting that binding of p53 and
htt is … expression of httex1p has an effect upon transcription of genes regulated by p53. The …

RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

K Mazan-Mamczarz, S Galbán… - Proceedings of the …, 2003 - National Acad Sciences
… of the RNA-binding protein HuR in a UVC-… expressing reduced HuR showed markedly
diminished p53 abundance and p53 translation. Our results demonstrate a role for HuR in binding

Cap and cap‐binding proteins in the control of gene expression

I Topisirovic, YV Svitkin, N Sonenberg… - Wiley Interdisciplinary …, 2011 - Wiley Online Library
protein cap‐binding proteinbinding proteins in the regulation of gene expression. We also
describe emerging regulatory pathways that control mRNA capping and cap‐binding proteins

SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein α transcriptional complex

L Qiao, J Shao - Journal of Biological Chemistry, 2006 - ASBMB
… We propose that low expression of SIRT1 and Foxo1 leads to impaired Foxo1-C/EBPα
complex formation, which contributes to the diminished adiponectin expression in obesity and …

The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

AN Ladd, N Charlet-B, TA Cooper - Molecular and cellular biology, 2001 - Am Soc Microbiol
… The KH-type RNA binding protein Nova-1 is expressed … Brain polypyrimidine tract binding
protein (brPTB), a protein … The importance of CELF family function is probably not diminished

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

W Dai, G Zhang, EV Makeyev - Nucleic acids research, 2012 - academic.oup.com
… The T7-HuR overexpression diminished the expression of the endogenous HuR to a
dramatically low level as compared to the control transgenic cells lacking the T7-HuR gene ( Figure …