Association of body-shape phenotypes with imaging measures of body composition in the UK Biobank cohort: relevance to colon cancer risk

S Christakoudi, KK Tsilidis, E Evangelou, E Riboli - BMC cancer, 2021 - Springer
… subset of UK Biobank participants, we examined the body-composition profile of body-shape
examined in the complete cohort the association between body-shape phenotypes and the …

A Body Shape Index (ABSI), hip index, and risk of cancer in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - Cancer …, 2021 - Wiley Online Library
… NHANES, we derived coefficients from UK Biobank data (Supplementary Methods). To
illustrate differences with traditional body shape indices, we examined these individually and in …

Associations of A Body Shape Index (ABSI) with Cancer Incidence, All-Cause, and at 23 Sites—Findings from the UK Biobank Prospective Cohort Study

S Parra-Soto, FC Malcomson, FK Ho, JP Pell… - … Biomarkers & Prevention, 2022 - AACR
Background: Few studies have explored the emerging adiposity marker A Body Shape Index
(ABSI) with cancer risk. This study investigated the associations between ABSI and the …

Associations of body shape index (ABSI) and hip index with liver, metabolic, and inflammatory biomarkers in the UK Biobank cohort

S Christakoudi, E Riboli, E Evangelou, KK Tsilidis - Scientific Reports, 2022 - nature.com
… phenotypes defined with ABSI and HI also provide information for body composition, with …
the UK Biobank cohort, we have examined the associations of body shape phenotypes based …

Associations of body shape phenotypes with sex steroids and their binding proteins in the UK Biobank cohort

S Christakoudi, E Riboli, E Evangelou, KK Tsilidis - Scientific Reports, 2022 - nature.com
… are correlated strongly with body size. We defined body shape using “a body shape index”
(… generalised linear models for the UK Biobank cohort (179,902 men, 207,444 women). Total …

GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer

S Christakoudi, E Evangelou, E Riboli, KK Tsilidis - Scientific reports, 2021 - nature.com
… It should first be acknowledged, that the UK Biobank cohort is not representative of the
UK … In addition, we lacked a validation cohort of similar ethnicity to the discovery dataset, …

Sex differences in the associations of body size and body shape with platelets in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - Biology of sex …, 2023 - Springer
… Clarifying the associations of body shape with platelets matters, because the … In this study,
we have used UK Biobank data to examine the association of body size and body shape, …

Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - BMC Endocrine …, 2023 - Springer
… of body mass index (BMI) and the allometric body shape index (… (SD) scale) in UK Biobank
participants without known metabolic, … We additionally defined body shape phenotypes with …

Multi-trait body shape phenotypes and breast cancer risk in postmenopausal women: a causal mediation analysis in the UK Biobank cohort

A Amadou, H Freisling, AM Sedlmeier… - Journal of Epidemiology …, 2024 - Springer
… Our findings are consistent with differential pathways linking different body shapes with BC
… obese body shape and BC risk, while IGF-1 and SHBG may mediate a tall/lean body shape-…

Interactions of obesity, body shape, diabetes and sex steroids with respect to prostate cancer risk in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - Cancer …, 2024 - Wiley Online Library
… A clear strength of our study is the prospective cohort design … HI as the appropriate indices
of body shape, since by design … of central body obesity such as the waist-to-height ratio, body