… are in agreement with the expected outcome of EGFR inhibition. Finally, the molecular docking
of 7g and 7m in the active site of EGFR revealed a common binding pattern similar to that …

… the EGFR inhibitors discussed in this review. … EGFR inhibitors which target EGFR with high
selectivity such as gefitinib; (2) dual EGFR inhibitors such as lapatinib which can target EGFR …

… EGFR inhibitors. All the target compounds were tested for inhibitory effects against wild type
EGFR (EGFR … compound 4c could closely interact with EGFR. Generally, compound 4c was …

… EGFR inhibitors. The derivatives that exhibited promising EGFR inhibitory effects were further
assessed … The candidate which revealed characteristic EGFR inhibition and showed potent …

… In the present study we have identified dual EGFR/c-Met inhibitors … EGFR kinases in
nanomolar range. We have demonstrated by Western blot analysis that compound 10 inhibits EGFR …

… as EGFR inhibitors affecting both MCF-7 and HepG2 cancer cell lines using MTT assay.
Newly synthesized compounds were assessed for their potential inhibition against EGFR. Most …

… from irreversible EGFR inhibitors is a … EGFR inhibitor 9n did not display obvious inhibition
on the growth of A549, SW620, and K562 cancer cells, all of which have low levels of EGFR …

… features of EGFR inhibitors are required for maximum affinity against the EGFR ATP binding
… many anticancer molecules through the inhibition of diverse RTKs including EGFR 22,23 . In …

… However, we found no indications that this drug can work better than other EGFR inhibitors.
Instead, results of a phase III study showed that patients with advanced NSCLC after prior …

… -target inhibitors against both FGFR4 and EGFR by artificial … of dual-target inhibitors by
molecular dynamics simulation. … for inhibitor activity prediction against FGFR4 and EGFR. Then, …