Design, facile synthesis and biological evaluations of novel pyrano [3, 2-a] phenazine hybrid molecules as antitumor agents

Y Lu, Y Yan, L Wang, X Wang, J Gao, T Xi… - European Journal of …, 2017 - Elsevier
… and pyran pharmocophores, were facilely synthesized in two steps with 77–93% overall
yields in this study. Cytotoxic evaluation indicates that many compounds exhibited cytotoxicity …

Coumarin‐based bioactive compounds: facile synthesis and biological evaluation of coumarin‐fused 1, 4‐thiazepines

M Khoobi, A Foroumadi, S Emami… - Chemical Biology & …, 2011 - Wiley Online Library
synthesis of bioactive coumarin compounds, we synthesized a series of new coumarin-fused
1,4-thiazepines using a simple method. The biological … was screened by evaluation of their …

Facile synthesis and biological evaluation of New Mannich products as potential antibacterial, antifungal and antituberculosis agents: molecular docking study

HM Patel, KD Patel, HD Patel - Current Bioactive Compounds, 2017 - ingentaconnect.com
Background: In these study we report here one-pot multi-component and solvent free
Mannich reaction of UV absorbing material, five member heterocyclic ring system and amides/…

Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation

DD Subhedar, MH Shaikh, BB Shingate… - European Journal of …, 2017 - Elsevier
… The results of the biological evaluation reveal that the activity was considerably affected by
introducing a various substituents on quinoline ring and the homologation of -CH 2 group in …

Facile synthesis, biological evaluation and molecular docking studies of novel substituted azole derivatives

M Rafiq, M Saleem, F Jabeen, M Hanif, SY Seo… - Journal of Molecular …, 2017 - Elsevier
… ,2,4-triazole nucleus have attracted great and growing interest in chemistry and biology for
many years due to their facile synthesis and broad range of biological activities [38], [39], [40], […

Facile synthesis of new N-sulfonamidyl-4-thiazolidinone derivatives and their biological evaluation

DD Subhedar, MH Shaikh, FAK Khan… - New Journal of …, 2016 - pubs.rsc.org
… of our studies based on synthesis and bioevaluation, 27 herein we report the synthesis of
new … -free heterocyclic synthesis conditions in high yields. In addition to this, we screened the …

Facile synthesis, structural activity relationship, molecular modeling and in vitro biological evaluation of new urea derivatives with incorporated isoxazole and thiazole …

FM Sroor, AM Abdelmoniem, IA Abdelhamid - ChemistrySelect, 2019 - Wiley Online Library
synthesized, fully characterized and evaluated in vitro as anticancer agents. The chemistry
involves a facile … The cytotoxicity of the synthesized compounds 12–22 were evaluated using …

[PDF][PDF] Design, facile synthesis, and biological evaluation of novel 1, 3-thiazine derivatives as potential anticonvulsant agents

N Deshmukhi - Asian J Pharm Clin Res, 2016 - researchgate.net
Synthesis and biological evaluation of some heterocyclic derivatives of chalcones. J Chem
Synthesis and biological evaluation of some biphenyl ether and thiazine derivatives. Indian J …

Facile synthesis and biological evaluation of assorted indolyl-3-amides and esters from a single, stable carbonyl nitrile intermediate

CGL Veale, AL Edkins, JA de la Mare, C de Kock… - Tetrahedron …, 2015 - Elsevier
… Following synthesis and characterization, our cohort of amides and esters was subjected
to biological assessment against a chloroquine-sensitive malarial strain (NF54), a breast …

A facile synthesis of some 3-cyano-1,4,6-trisubstituted-2(1H)-pyridinones and their biological evaluation as anticancer agents

SAF Rostom, HM Faidallah, MS Al-Saadi - Medicinal Chemistry Research, 2011 - Springer
… )-pyridinones and their biological evaluation as anticancer agents | SpringerLink … facile
synthesis of some 3-cyano-1,4,6-trisubstituted-2(1H)-pyridinones and their biological evaluation