… PI3K/AKT/mTOR signalling cascade is also involved in miRNA biogenesis and biological …
Therefore, there is great potential for regulatory miRNAs of the PI3K/AKT/mTOR signalling …

… permeability, and whereas the impacts of the PI3K/AKT pathway on apoptosis are comprehensive.
… Due to its participation in several biological functions, the PI3K/AKT pathway is now …

… activation of Akt and stress-induced activation of the PI3K/Akt pathway accelerate the repair
… The impact of PI3K/Akt activity on radioresistance has been reported by several laboratories …

… biology of these mutated proteins may impact the … PI3K/AKT signaling appears to be critical
to prostate cancer cell survival and proliferation. Our increasing understanding of the biology …

… therapeutic inhibition of the PI3K-AKT-mTOR signaling network … discuss how PI3K-AKT-mTOR
inhibitors not only impact directly … We next discuss how PI3K-AKT-mTOR inhibitors can be …

… mTORC2 acts as an upstream regulator of AKT, and … A dysregulated activation of mTOR, as
result of PI3K pathway or mTOR … In the final part of this review, we will focus on the PI3K/AKT/…

… In this paper, after a general overview of the biological significance and the main components
of these pathways, we address the present status of the development of specific PI3K, Akt, …

… (PI3K) pathway. Since breast cancer cell growth and progression is often dependent upon
activation of the PI3K … Here we review key molecules involved with aberrant PI3K pathway …

… p53 signaling network, the PI3K/Akt/mTOR cascade is … PI3K, Akt and second generation
mTOR inhibitors are in early clinical trials. We propose to provide a brief overview of the PI3K/Akt/…

… The combination of PI3K/AKT/mTOR inhibitors with radiation … Therefore, this review aims to
discuss the impact of such … 3-kinase/AKT (PI3K/AKT) signaling pathway is closely paired with …