[HTML][HTML] Mechanical stress promotes biological functions of C2C12 myoblasts by activating PI3K/AKT/mTOR signaling pathway
Y Da, Y Mou, M Wang, X Yuan… - Molecular …, 2020 - spandidos-publications.com
… specific inhibitor LY294002 significantly decreased 4EBP1 expression and reduced p‑AKT
and … stress promoted biological functions of C2C12 cells by activating the PI3K/AKT signaling …
and … stress promoted biological functions of C2C12 cells by activating the PI3K/AKT signaling …
mTORC1 inhibition and ECM–cell adhesion-independent drug resistance via PI3K–AKT and PI3K–RAS–MAPK feedback loops
K Galoian, HT Temple, A Galoyan - Tumor biology, 2012 - Springer
… PRP-1 is not an HDAC inhibitor in chondrosarcoma and that is why AKT is not getting
dephosphorylated after the PI3K–AKT feedback loops are triggered as a consequence of mTORC1 …
dephosphorylated after the PI3K–AKT feedback loops are triggered as a consequence of mTORC1 …
EGFR–PI3K–AKT–mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy
C Freudlsperger, JR Burnett, JA Friedman… - Expert opinion on …, 2011 - Taylor & Francis
… of EGFR–PI3K–Akt–mTOR signaling in HNSCC, including the impact of both genetic and …
; however, more studies are still needed to better understand the biology of this pathway. …
; however, more studies are still needed to better understand the biology of this pathway. …
[HTML][HTML] Effects of GLP-1 receptor agonists on biological behavior of colorectal cancer cells by regulating PI3K/AKT/mTOR signaling pathway
G Tong, T Peng, Y Chen, L Sha, H Dai… - Frontiers in …, 2022 - frontiersin.org
… of the PI3K/Akt/mTOR signaling pathway on cell biology, we … of CRC cells by mediating
PI3K/Akt/mTOR. Therefore, this … effects of liraglutide on the PI3K/Akt/mTOR signal pathway and …
PI3K/Akt/mTOR. Therefore, this … effects of liraglutide on the PI3K/Akt/mTOR signal pathway and …
[HTML][HTML] The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT signaling
BY Shorning, MS Dass, MJ Smalley… - International journal of …, 2020 - mdpi.com
… of the broader PI3K-AKT-mTOR signaling network is crucial to aid patient stratification for
PI3K-AKT-… However, the impact on the PI3K-AKT-mTOR signaling cascade remains unclear. …
PI3K-AKT-… However, the impact on the PI3K-AKT-mTOR signaling cascade remains unclear. …
The role of Her2 and other oncogenes of the PI3K/AKT pathway in mitochondria
K Rohlenova, J Neuzil, J Rohlena - Biological Chemistry, 2016 - degruyter.com
… Hyperactivation of pro-survival and pro-proliferative pathways such as PI3K/AKT leads to …
as the downstream members of the PI3K/AKT signaling pathway, directly regulate mitochondria …
as the downstream members of the PI3K/AKT signaling pathway, directly regulate mitochondria …
[HTML][HTML] Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and …
B Fourneaux, V Chaire, C Lucchesi, M Karanian… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… S6K-mTORC2-AKT negative feedback loops. … PI3K and mTOR in human leiomyosarcomas
on anti-tumor activity, especially the biological consequences on components of the PI3K/AKT…
on anti-tumor activity, especially the biological consequences on components of the PI3K/AKT…
MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology
… -21, PTEN, and the PI3K/AKT signaling, shedding light on their … and its consequent impact
on PI3K/AKT pathway activation. It … of miR-21's impact on PTEN, PI3K/AKT cascade, and the …
on PI3K/AKT pathway activation. It … of miR-21's impact on PTEN, PI3K/AKT cascade, and the …
[HTML][HTML] SERPIND1 affects the malignant biological behavior of epithelial ovarian cancer via the PI3K/AKT pathway: a mechanistic study
Q Guo, L Zhu, C Wang, S Wang, X Nie, J Liu… - Frontiers in …, 2019 - frontiersin.org
… PI3K/AKT pathway and promote the malignant biological behavior of ovarian cancer cells
(Figure 6). Our results ultimately showed that SERPIND1 could be an effective early diagnostic …
(Figure 6). Our results ultimately showed that SERPIND1 could be an effective early diagnostic …
[HTML][HTML] Tumor‑associated macrophages affect the biological behavior of lung adenocarcinoma A549 cells through the PI3K/AKT signaling pathway
S Yuan, Y Dong, L Peng, M Yang, L Niu… - Oncology …, 2019 - spandidos-publications.com
… affect the biological activity of lung cancer cells by activating the PI3K/AKT signaling pathway.
In … , the expression levels of t-PI3K, t-AKT and corresponding phosphorylated p-AKT and p-…
In … , the expression levels of t-PI3K, t-AKT and corresponding phosphorylated p-AKT and p-…