Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

M Lundqvist, J Stigler, G Elia, I Lynch… - Proceedings of the …, 2008 - National Acad Sciences
… Here, we study the long-lived (“hard”) protein corona formed from human plasma for a …
and size on the detailed protein coronas. Proteins in the corona that are conserved and unique …

Physical−Chemical Aspects of Protein Corona: Relevance to in Vitro and in Vivo Biological Impacts of Nanoparticles

MP Monopoli, D Walczyk, A Campbell… - Journal of the …, 2011 - ACS Publications
… show that the major contribution to the protein corona thickness is from proteins in the 70−50
kDa range that are predominant in both PSOSO 3 and SiO 2 NP protein coronas (Figure 4). …

The impact of protein corona on the biological behavior of targeting nanomedicines

M Farshbaf, H Valizadeh, Y Panahi, Y Fatahi… - International Journal of …, 2022 - Elsevier
… from a phenomenon called “protein corona (PC) formation” … proteins with high collision
frequency. This phenomenon endows the targeting nanomedicines with a different biological

Nanoparticle protein corona evolution: from biological impact to biomarker discovery

N Kamaly, OC Farokhzad, C Corbo - Nanoscale, 2022 - pubs.rsc.org
… or protein corona, once thought of as problematic biofouling, is now viewed as a rich source
of biological … This review gives an overview of the utility of the protein corona in proteomic …

Biological identity of nanoparticles in vivo: clinical implications of the protein corona

G Caracciolo, OC Farokhzad, M Mahmoudi - Trends in biotechnology, 2017 - cell.com
… a biological milieu are covered by a dynamic coating of biomolecules referred to as a protein
corona … proposed an alternative model that describes the PC as comprising protein clouds [ …

Biological impacts of reduced graphene oxide affected by protein corona formation

R Coreas, C Castillo, Z Li, D Yan, Z Gao… - Chemical research in …, 2022 - ACS Publications
… the uptake of the corona-coated materials by labeling the protein corona with fluorescein …
the labeling of nanomaterials pre-coated with a protein corona (53) to facilitate cellular uptake …

Impact of protein corona on the biological identity of nanomedicine: understanding the fate of nanomaterials in the biological milieu

MH Akhter, H Khalilullah, M Gupta, MA Alfaleh… - Biomedicines, 2021 - mdpi.com
… from the NP–protein corona complex although it is not a part of corona composition. The
large surface area aggregates of the corona with diversified proteins have been explained in …

Formation of a protein corona influences the biological identity of nanomaterials

D Nierenberg, AR Khaled… - Reports of Practical …, 2018 - journals.viamedica.pl
Protein corona: impact of lymph versus blood in a complex in vitro environment. Small
2017;13(29), http://dx.doi.org/10.1002/smll.201700409. 21. Docter D, Westmeier D, Markiewicz M, …

Impact of silica nanoparticle surface chemistry on protein corona formation and consequential interactions with biological cells

A Kurtz-Chalot, C Villiers, J Pourchez… - Materials Science and …, 2017 - Elsevier
… Moreover, the biological in vitro toxicity was not correlated with … protein corona and clearly
argues for its systematic consideration in nanotoxicology studies as it defines the biological

Merging worlds of nanomaterials and biological environment: factors governing protein corona formation on nanoparticles and its biological consequences

P Foroozandeh, AA Aziz - Nanoscale Research Letters, 2015 - Springer
biological environment in which the NPs are dispersed. It is noteworthy to mention that the cell
perceives protein corona … Thus, understanding protein corona which confers the biological