Emerging insights into pyrazoline motifs: A comprehensive exploration of biological mechanisms and prospects for future advancements

HA Abou-Zied, EAM Beshr, AM Hayallah… - Journal of Molecular …, 2023 - Elsevier
… In this comprehensive literature review spanning the last six months, we explore the … for
drug development targeting several key biological macromolecules, including TMK, AChE, MAO, …

Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration

E Afshinnekoo, RT Scott, MJ MacKay, E Pariset… - Cell, 2020 - cell.com
Research on astronaut health and model organisms have revealed six features of spaceflight
biology that guide our current understanding of fundamental molecular changes that occur …

[HTML][HTML] Exploring Molecular Mechanisms and Biomarkers in COPD: An Overview of Current Advancements and Perspectives

CL Li, SF Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
… by granting the comprehensive molecular profiling of biological systems across various levels…
These omics methodologies offer a comprehensive view of disease pathogenesis, facilitate …

Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle

L Fang, W Cai, S Liu, O Canela-Xandri, Y Gao… - Genome …, 2020 - genome.cshlp.org
biological mechanisms underlying complex traits in cattle, and our transcriptome atlas can
serve as a primary source for biological … To further explore which brain regions were relevant …

[HTML][HTML] Unraveling NEAT1's complex role in lung cancer biology: a comprehensive review

MS Hussain, O Afzal, G Gupta, A Goyal, WH Almalki… - EXCLI …, 2024 - ncbi.nlm.nih.gov
… engagement in LC biology positions it as a potential therapeutic target and diagnostic tool.
Further research is necessary to unravel its intricate mechanisms and explore its therapeutic …

A Comprehensive Exploration of Bioluminescence Systems, Mechanisms, and Advanced Assays for Versatile Applications

AN Dunuweera, SP Dunuweera… - Biochemistry …, 2024 - Wiley Online Library
… , circumventing cell lysis and enabling the exploration of cell viability. The secNluc gene has
… . studied a comprehensive protocol to measure the ATP concentration in biological systems …

[HTML][HTML] A comprehensive review of cycloastragenol: Biological activity, mechanism of action and structural modifications

M He, K Wang, H Che, H Wang, K Yang… - European Journal of …, 2022 - Elsevier
… clinic, focusing on the extensively biological activities as well as the mechanism of action and
… CAG are also described for further druggability exploration to provides valuable reference. …

Exploring the Biological Pathways of Siderophores and Their Multidisciplinary Applications: A Comprehensive Review

B Xie, X Wei, C Wan, W Zhao, R Song, S Xin, K Song - Molecules, 2024 - mdpi.com
explore the secretion mechanisms of siderophores in microbes and plants, and their role in
regulating bioavailable iron levels. Beyond biological … These applications include biological

Polymorphic toxin systems: comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative …

D Zhang, RF de Souza, V Anantharaman, LM Iyer… - Biology direct, 2012 - Springer
… most of the levels of biological conflict enumerated above are … the exploration of several
alternative secretory mechanisms … at least eight distinct secretory mechanisms over and beyond …

Comprehensive exploration of Biochanin A as an oncotherapeutics potential in the treatment of multivarious cancers with molecular insights

M Sohel - Phytotherapy Research, 2024 - Wiley Online Library
… The biological mechanism responsible for the emergence of chemoresistance varies
according to cancer types and the nature of drugs. P-glycoprotein (P-gp) is a multidrug resistance …