Accumulating evidence supports a taste component for free fatty acids in humans

RD Mattes - Physiology & behavior, 2011 - Elsevier
… , light, and heat and results in a host of compounds with adverse biological effects. Oxidized
… in polymorphonuclear cells and may mediate the effects of short chain fatty acids on immune …

The endocrinology of taste receptors

SSC Calvo, JM Egan - Nature Reviews Endocrinology, 2015 - nature.com
… the biological mechanisms that underpin taste perception, … be the major mediators for these
tastes, other mechanisms for … considerably reduced preferences for fat taste. Moreover, mice …

Cell signaling mechanisms of oro-gustatory detection of dietary fat: advances and challenges

TA Gilbertson, NA Khan - Progress in lipid research, 2014 - Elsevier
… lipid mediators by the action of cyclooxygenase and lipoxygenase pathways [55], [56]. …
We think that it would take time for the scientific community to accept the fat taste modality. For …

Molecular mechanisms of taste recognition: considerations about the role of saliva

TK Fábián, A Beck, P Fejérdy, P Hermann… - International Journal of …, 2015 - mdpi.com
… receptors of the complementary taste modalities like “fat taste” or “fatty acid taste” [7] “CO 2 …
of tastants and various soluble taste perception-related mediators because of a dilution effect […

Ca2+ signaling in taste bud cells and spontaneous preference for fat: unresolved roles of CD36 and GPR120

S Abdoul-Azize, S Selvakumar, H Sadou, P Besnard… - Biochimie, 2014 - Elsevier
… perception, most of the dietary fat is present in the form of triglycerides. … be hydrolyzed into
free fatty acids which are initially responsible for fat taste. Radioactive … The cell biology of taste

Mechanisms of gustatory perception of dietary lipids: cross-talk with bitter taste and endocannabinoid receptors

L Brissard - 2018 - theses.hal.science
taste with lipid taste. This thesis consists of two components: cannabinoid (CB1R) and bitter
taste … We report that CB1R is involved in the perception of fat taste via calcium signalling and …

Fat sensation: Fatty acid taste and olfaction sensitivity and the link with disinhibited eating behaviour

S Kindleysides, KL Beck, DCI Walsh, L Henderson… - Nutrients, 2017 - mdpi.com
… to play a role in signaling pathways that mediate fatty acid detection in the gut [91,93]. …
in turn generates inconsistencies about the potential biological or functional relationships [19,31]. …

Chemosensory Aspects in Obesity: Rethinking the Role of Sweet and Fat Taste

RM Armitage, V Iatridi, MR Yeomans - Smell, Taste, Eat: The Role of the …, 2024 - Springer
fat taste, distinguishing between oral detection of specific free fatty acids (FFAs) (ie, fattaste
, in rodents, CD36 is localised to taste buds, reacts to FFAs, and has been shown to mediate

Role of endocannabinoids on sweet taste perception, food preference, and obesity-related disorders

E Tarragon, JJ Moreno - Chemical Senses, 2018 - academic.oup.com
… of arachidonic acid (AA), resembling other lipid mediators such as prostaglandins and
leukotrienes. AA is conjugated with ethanolamine to form fatty acid amides or with glycerol to form …

Novel Perspective on the Plasticity of Taste Perception: Is Food-and Exercise-Induced Inflammation Associated with Sweet Taste Sensitivity and Preference?

I Kimmeswenger, B Lieder - Journal of Agricultural and Food …, 2024 - ACS Publications
taste modalities, among them being fatty, kokumi, or the ability to detect essential nutrients,
such as Ca 2+ . (2) Taste perception starts at the level of oral taste … pro-inflammatory mediator