Overcoming the bitter taste of oils enriched in fatty acids to obtain their effects on the heart in health and disease

A Stamenkovic, R Ganguly, M Aliani, A Ravandi… - Nutrients, 2019 - mdpi.com
… or anabolic for creating biologically important molecules from dietary sources of fatty acids.
… oxygenation and are transformed into short term lipid mediators known as oxylipins [20]. …

Genetic Sensitivity to the Bitter Taste of 6-n-Propylthiouracil (PROP) and Its Association with Physiological Mechanisms Controlling Body Mass Index (BMI)

BJ Tepper, S Banni, M Melis, R Crnjar… - Nutrients, 2014 - mdpi.com
… In addition, the ability to taste fatty acids has been recently … Local projections from the NST
within the brainstem mediate non-… How the taste signals integrated within taste buds are …

[PDF][PDF] Mechanism of fat taste and its relationship with obesity

D Liu - 2018 - dro.deakin.edu.au
… Expression of candidate fat taste receptors in human fungiform papillae and the association
with fat taste function. This paper is currently accepted by the British Journal of Nutrition. …

Role of gut nutrient sensing in stimulating appetite and conditioning food preferences

A Sclafani, K Ackroff - American Journal of Physiology …, 2012 - journals.physiology.org
… acid receptor elements, including CD36, GPR120, and GPR40 have been proposed to
mediate fatty acid taste (94). Critical evidence that CD36 is involved in fatty acid taste was …

Orosensory perception of dietary lipids in mammals

P Passilly-Degrace, D Gaillard, P Besnard - Chemosensory Systems in …, 2009 - Springer
… to PUFA of taste cells may contribute to fat preference, thereby … The key question at this
stage concerned the possible mediation … The identification of relevant, non-invasive biological

Taste transductions in taste receptor cells: basic tastes and moreover

S Iwata, R Yoshida, Y Ninomiya - Current pharmaceutical …, 2014 - ingentaconnect.com
… Recent molecular biological studies have proposed … of five basic tastes, fat taste and calcium
taste in taste receptor cells. … Thus, both GPR120 and GPR40 may mediate the taste of fatty

Molecular mechanisms of bitter and sweet taste transduction

RF Margolskee - Journal of Biological Chemistry, 2002 - ASBMB
… qualities: fat and amino acid taste. … taste receptor cells underlying bitter and sweet taste
qualities. All transduction pathways are proposed to converge on common elements that mediate

Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors

BR Simon, SD Parlee, BS Learman, H Mori… - Journal of Biological …, 2013 - ASBMB
mediate responses to a myriad of ligands, some of which regulate adipocyte differentiation
and metabolism. The sweet taste … role as has been demonstrated by fatty acids acting through …

Expression of the candidate fat taste receptors in human fungiform papillae and the association with fat taste function

D Liu, A Costanzo, MDM Evans, NS Archer… - British Journal of …, 2018 - cambridge.org
… that all these papillae contain the biological machinery for fat taste detection. The … , albeit
through different mediators(11). Although controversies arose when it was shown that the …

GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse

A Sclafani, S Zukerman… - American Journal of …, 2013 - journals.physiology.org
… there is accumulating evidence that dietary fat is detected by fatty acid taste … “fat taste
contributes to the palatability of high-fat foods (23). Three candidate fat taste receptors are the fatty