… targeted by therapies for various disorders. A better understanding of the biology of autophagy
and the pharmacology of … -based therapeutic interventions for several human diseases. …

Human fatty acid synthase (FASN) is a 270-kDa cytosolic dimeric enzyme that is responsible
for palmitate synthesis. FASN is slowly emerging and rediscovered as a marker for …

… While describing and discussing the findings obtained with these approaches, we will
compare the actions of these various pharmacological and biological tools with those obtained …

… This Review provides an overview of the biological roles and therapeutic potential of proprotein
… challenges in the development of novel proprotein convertase-targeted therapeutics. …

… C (VC) exerts potent pharmacological activities against liver … pharmacology-based strategy
to predict therapeutic targets of VC against LI, and further to investigate the pharmacological …

Liver fibrosis represents the generic wound healing response to chronic insults regardless
of their mechanism. The causes of chronic liver injury and fibrosis have a wide geographic …

… Considering that a comprehensive review on the pharmacological modulation of brain NCX
… the molecular pharmacology of NCX in the brain and the possible therapeutic implications of …

… Its biological role has been controversial with initial reports purporting atheroprotective effects
of … ; however, more studies are needed to better define the biological role of this enzyme. …

… pharmacology. The two liver X receptors LXRα and LXRβ are among the emerging newer
drug targets within … , they have potential as therapeutic targets for diseases as diverse as lipid …

… , limited structural information is available to understand their binding to RAS or RAL, thus
structural studies will be needed before they can be exploited as feasible therapeutic targets …