Targeting the tumor microenvironment in renal cell cancer biology and therapy
I Heidegger, A Pircher, R Pichler - Frontiers in oncology, 2019 - frontiersin.org
Renal cell cancer (RCC) is a highly vascularized and immunogenic tumor type. The inhibition
of vessel formation by anti-angiogenic therapies, as well as the stimulation of the immune …
of vessel formation by anti-angiogenic therapies, as well as the stimulation of the immune …
The nephrologist's tumor: basic biology and management of renal cell carcinoma
SL Hu, A Chang, MA Perazella, MD Okusa… - Journal of the …, 2016 - journals.lww.com
… Tumor Resection and Ablative Therapies RN remains the conventional therapy for large
renal masses and nonlocalized tumors… therapies, are emerging as mainstream therapies for …
renal masses and nonlocalized tumors… therapies, are emerging as mainstream therapies for …
[PDF][PDF] Pathology of renal tumors in adults. molecular biology, histopathological diagnosis and prognosis
K Okoń - Pol J Pathol, 2008 - Citeseer
… In our material [282], 97 renal tumor autopsies were seen in 3512 postmortem exams.
Half of the detected tumors were benign; among the malignant tumors, the papillary type was …
Half of the detected tumors were benign; among the malignant tumors, the papillary type was …
Tumor biology and prognostic factors in renal cell carcinoma
DS Finley, AJ Pantuck, AS Belldegrun - The oncologist, 2011 - academic.oup.com
… biology that have provided insight into the alterations underlying these renal cortical tumor
… understanding of these renal cortical tumors, the crucial biological pathways that become …
… understanding of these renal cortical tumors, the crucial biological pathways that become …
mTOR in renal cell cancer: modulator of tumor biology and therapeutic target
PJ Wysocki - Expert review of molecular diagnostics, 2009 - Taylor & Francis
… Since the biology of renal cell cancer (RCC) is tightly controlled by mTOR, targeted … in
RCC biology as well as clinical efficacy of mTOR inhibitors in the treatment of renal cell cancer. …
RCC biology as well as clinical efficacy of mTOR inhibitors in the treatment of renal cell cancer. …
[HTML][HTML] Biology and treatment of renal tumours in childhood
J Brok, TD Treger, SL Gooskens… - European Journal of …, 2016 - Elsevier
… This review provides a comprehensive overview of the current biological knowledge of
childhood renal tumours alongside the progress achieved through international collaboration. …
childhood renal tumours alongside the progress achieved through international collaboration. …
Renal cell carcinoma of variant histology: biology and therapies
P Msaouel, G Genovese… - Hematology/Oncology …, 2023 - hemonc.theclinics.com
… subtypes such as renal medullary carcinoma and … tumors. Herein, we provide guidance on
how to choose appropriate treatment of vhRCCs based on our evolving clinical and biological …
how to choose appropriate treatment of vhRCCs based on our evolving clinical and biological …
Renal cell carcinoma: new developments in molecular biology and potential for targeted therapies
LJ Costa, HA Drabkin - The oncologist, 2007 - academic.oup.com
… insufficient to generate tumors [20], HIF continues to play an important role in the tumorigenicity
of established RCCs [21]. Disruption of translocation in renal carcinoma, chromosome 8 …
of established RCCs [21]. Disruption of translocation in renal carcinoma, chromosome 8 …
The molecular biology of renal cell carcinoma
SM Keefe, KL Nathanson, WK Rathmell - Seminars in oncology, 2013 - Elsevier
… renal cancer field to leverage new knowledge into developing diagnostic and therapeutic …
to be diagnosed with cancer of the kidney and renal pelvis in 2013, and 13,680 are estimated …
to be diagnosed with cancer of the kidney and renal pelvis in 2013, and 13,680 are estimated …
Renal cell carcinoma: biological features and rationale for molecular-targeted therapy
M Oya - The Keio Journal of Medicine, 2009 - jstage.jst.go.jp
… Accordingly, a popular strategy for molecular-targeted therapy for RCC targets the …
highlights the biological features of RCC that are rel- evant to molecular-targeted therapy. (…
highlights the biological features of RCC that are rel- evant to molecular-targeted therapy. (…
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