[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…
viral life cycle is a feasible approach for treating COVID-19. Belonging to the subfamily …

[HTML][HTML] Chemistry and biology of SARS-CoV-2

A Dömling, L Gao - Chem, 2020 - cell.com
… The SARS-CoV-2 pandemic has changed our world in just half a year: a large number of
people have died from the virus-induced pneumonia COVID-19, and the global economy is at …

The evolution and biology of SARS-CoV-2 variants

A Telenti, EB Hodcroft… - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
… with circulating SARS-CoV-2. Here, we review current knowledge of the biological properties
of amino acid replacements in SARS-CoV-2 proteins, SARS-CoV-2 lineages and VOCs, …

[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
… a few months after the appearance of SARS-CoV-2 at the end of 2019 … , COVID-19. In
this Review, we discuss key aspects of coronavirus biology and their implications for SARS-CoV-2

[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
COVID-19 are urgently needed, and the structures of the potential drug-target proteins in the
viral life cycle are particularly important. SARS-CoV-2, a … that target SARS-CoV-2 or some …

[PDF][PDF] The biology of SARS-CoV-2 and the ensuing COVID-19

S Anastasopoulou, A Mouzaki - Achaiki Iatriki, 2020 - ispyrgou.gr
… the epidemiological characteristics of the novel coronavirus SarS-coV-2 differ dramatically
from those of the previous coronavirus outbreaks, SarScoV in 2002-2003 and MerS-coV in …

Understanding the molecular biology of SARS-CoV-2 and the COVID-19 pandemic: A review

S Alsobaie - Infection and Drug Resistance, 2021 - Taylor & Francis
SARS pandemic of all time. Here, I review the current understanding of the molecular biology
… therapeutic drugs and/or vaccines against SARS-CoV-2. I also briefly overview the current …

[HTML][HTML] The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
… evolution, the structure and function of the SARS-CoV-2 spike protein and the laboratory
methods used to characterize spike variants. We then describe the biological properties and …

[HTML][HTML] SARS-CoV-2: structure, biology, and structure-based therapeutics development

MY Wang, R Zhao, LJ Gao, XF Gao… - Frontiers in cellular …, 2020 - frontiersin.org
… of the caused disease COVID-19. We further discussed the biology of SARS-CoV-2, including
the origin, evolution, and receptor recognition mechanism of SARS-CoV-2. And particularly…

[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
coronavirus 2 (SARS-CoV-2) exhibited a major step change in its adaptation to humans.
These highly mutated forms of SARS-CoV-2 … complex interplay of virus biology in the context of …