The human connectome in Alzheimer disease—relationship to biomarkers and genetics

M Yu, O Sporns, AJ Saykin - Nature Reviews Neurology, 2021 - nature.com
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease

J Stevenson-Hoare, A Heslegrave, G Leonenko… - Brain, 2023 - academic.oup.com
… the biomarkers and Alzheimer’s disease genetic risk, age at onset and disease duration. …
genome-wide association study for association of disease risk genes with these biomarkers. …

Biomarkers of Alzheimer disease

JH Growdon - Archives of neurology, 1999 - jamanetwork.com
… Other CSF markers, such as neuronal thread protein, have been proposed as biomarkers
from an ideal biomarker for AD? It is probably unrealistic to expect that any biomarker be 100% …

Blood-based protein biomarkers for diagnosis of Alzheimer disease

…, Alzheimer's Disease Neuroimaging Initiative… - Archives of …, 2012 - jamanetwork.com
… fluid biomarker signature in Alzheimer's disease … a list of biomarkers identified within the
Alzheimer Disease … panel of blood-based biomarker candidates obtained by comparing …

Use of genetic variation as biomarkers for Alzheimer's disease

C Reitz, R Mayeux - Annals of the New York Academy of …, 2009 - Wiley Online Library
… of genetic variation as diagnostic tools and biomarkers in LOAD and discuss the potentials
and difficulties researchers face in designing appropriate studies for gene discovery. …

A genetics-based biomarker risk algorithm for predicting risk of Alzheimer's disease

…, Alzheimer's Disease Neuroimaging Initiative - Alzheimer's & Dementia …, 2016 - Elsevier
… age-dependent risk of Alzheimer's disease (AD) could be … performance of a genetics-based
biomarker risk algorithm (… it to cerebrospinal fluid (CSF) biomarkers, neuroimaging, and …

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

…, Alzheimer's Disease Neuroimaging Initiative - Alzheimer's & …, 2010 - Elsevier
… and planning group for genetics within the Alzheimer's Disease Neuroimaging Initiative.
Genome-… and Alzheimer's disease and GWAS of baseline cerebrospinal fluid biomarkers and …

Biomarkers in Alzheimer's disease: past, present and future

K Gustaw-Rothenberg, A Lerner, DJ Bonda… - Biomarkers in …, 2010 - Taylor & Francis
… Not only Aβ, but all of the major genetic and … disease pathogenesis Citation[14–16]. In this
regard, transcriptional profiling of genes as a biomarker assay could potentially predict disease

Blood-based biomarkers for Alzheimer's disease: plasma Aβ40 and Aβ42, and genetic variants

R Mayeux, N Schupf - Neurobiology of aging, 2011 - Elsevier
… a biomarker for Alzheimer's disease that can … biomarkers but most frequently plasma amyloid
beta (Aβ)40 and Aβ42 while others have explored the use of genetic variants as biomarkers

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
… In the US alone, Alzheimer disease (AD) – the most frequent cause of … genetic factors. In
this review article, we provide an overview of the epidemiology of AD, review the biomarkers that …