Biomarkers for Alzheimer's diseaseclinical needs and application

D Galasko - Journal of Alzheimer's Disease, 2005 - content.iospress.com
… intervention and even towards prevention, biomarkers will gain significance as tools to aid
… and ultimately clinical practice. Keywords: Alzheimer’s disease, amyloid-β, biomarkers, tau …

Biomarkers for Alzheimer's disease: current status and prospects for the future

K Blennow, H Zetterberg - Journal of internal medicine, 2018 - Wiley Online Library
… we foresee an increased use of these diagnostic tests in clinical routine practice. The AD
CSF biomarker toolbox has been expanded with novel biomarkers reflecting additional aspects …

[HTML][HTML] Alzheimer's disease CSF biomarkers: clinical indications and rational use

E Niemantsverdriet, S Valckx, M Bjerke… - Acta neurologica …, 2017 - Springer
… AD CSF biomarkers, as well as on the current clinical indications and … use of CSF biomarkers
in daily clinical practice. The diagnosis of Alzheimer’s disease relies on different biomarker

[HTML][HTML] Biomarkers for Alzheimer's disease: context of use, qualification, and roadmap for clinical implementation

J Cummings, J Kinney - Medicina, 2022 - mdpi.com
… In this perspective, we review emerging biomarkers relevant to DMT drug development and
… advancing biomarkers for their use in clinical trials and their implementation in clinical care. …

Molecular biomarkers of Alzheimer's disease: progress and prospects

T Lashley, JM Schott, P Weston… - Disease models & …, 2018 - journals.biologists.com
disease and its related pathologies. We also highlight the biomarkers that are currently in
clinical use and … with applying these biomarkers for diagnostic and prognostic purposes of …

Biomarkers for Alzheimer's disease therapeutic trials

H Hampel, G Wilcock, S Andrieu, P Aisen… - Progress in …, 2011 - Elsevier
… forces on disease-modifying trials and on endpoints for Alzheimer's disease clinical trials. …
art regarding the best use of biological markers in Alzheimer's disease therapy trials and to …

Use of CSF biomarkers in Alzheimer's disease clinical trials

K Blennow, H Zetterberg - JNHA-The Journal of Nutrition, Health and …, 2009 - Springer
… ) biomarkers and their use in clinical trials with AD disease-modifying drug candidates. CSF
biomarkers … Core candidate neurochemical and imaging biomarkers of Alzheimer's disease. …

Biomarkers in Alzheimer's disease drug development

JL Cummings - Alzheimer's & Dementia, 2011 - Elsevier
… In this review, definitions of biomarkers are presented, the diverse uses of biomarkers
role of biomarkers to assess efficacy of AD therapeutics is described. Individual biomarkers are …

Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials

R Ossenkoppele, R van der Kant… - The Lancet …, 2022 - thelancet.com
biomarkers of tau pathology in Alzheimer's disease, and discuss whether and how these tau
biomarkers can support the clinical … and how tau biomarkers can improve clinical trials of tau-…

Clinical application of CSF biomarkers for Alzheimer's disease: From rationale to ratios

FH Bouwman, GB Frisoni, SC Johnson… - Alzheimer's & …, 2022 - Wiley Online Library
… In this paper, we consider whether and how physicians should use CSF biomarkers in … We
present clinical cases to examine how CSF biomarkers could inform clinical practice decisions…