Molecular biomarkers for human chemical carcinogen exposures

JD Groopman, TW Kensler - Chemical research in toxicology, 1993 - ACS Publications
tobaccospecific nitrosamines in human urine. This is an important finding because these
tobacco… made in two areas, biological markers of metabolism and indices ofDNA repaircapacity. …

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

JM Yuan, HH Nelson, SG Carmella, R Wang… - …, 2017 - academic.oup.com
… ’s nicotine metabolism capacity can directly influence their level of carcinogen exposure. …
The impact of CYP2A6 genotypes on NMR, cigarette smoking and biomarkers of tobacco

Peripheral Biomarkers of Tobacco-Use Disorder: A Systematic Review

DF Newton - medRxiv, 2019 - medrxiv.org
… studied biomarkers were those related to nicotine metabolism, the hypothalamic-pituitary-adrenal
(HPA) axis, and cardiovascular (CVD) risk. Nicotine metabolism … Conclusions Nicotine-…

Role of biomarkers in monitoring exposures to chemicals: present position, future prospects

WP Watson, A Mutti - Biomarkers, 2004 - Taylor & Francis
… on biomarkers for monitoring human exposure to chemicals. A particular emphasis is on
monitoring exposures to … Significant developments in the areas of new and existing biomarkers, …

A prospective cohort study of biomarkers of prenatal tobacco smoke exposure: the correlation between serum and meconium and their association with infant birth …

JM Braun, JL Daniels, C Poole, AF Olshan… - Environmental …, 2010 - Springer
… % of inhaled nicotine (NIC) from tobacco smoke is metabolized into cotinine … biomarkers of
tobacco smoke exposure since many cohorts only have the resources to collect one exposure

Secondhand smoke and nicotine exposure: a brief review

CTC Okoli, T Kelly, EJ Hahn - Addictive behaviors, 2007 - Elsevier
… and/or biomarkers of nicotine in the body were … of nicotine exposure from SHS. This
manuscript will then compare levels of nicotine produced by SHS exposure with levels of nicotine

Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate …

ML Goniewicz, MD Eisner… - Nicotine & Tobacco …, 2011 - academic.oup.com
… Two biomarkers of tobacco smoke exposure are specific to tobacco and can be measured
… NNK is metabolized in human body to NNAL, and this metabolite is further conjugated with …

Biochemical verification of tobacco use and abstinence: 2019 update

NL Benowitz, JT Bernert, J Foulds… - … and Tobacco …, 2020 - academic.oup.com
… the recognized biomarkers of tobacco exposure, including their … which each biomarker is
able to assess tobacco use after … differences in nicotine metabolism pathways compared to …

Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure

NL Benowitz, KM Dains, D Dempsey… - Nicotine & Tobacco …, 2011 - academic.oup.com
… NNK is metabolized in the body to 4-(methylnitrosamino)-1-… biomarkers of nicotine intake
for carcinogen exposure, we performed cross-correlations among CPD and various biomarkers

Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol

ML Goniewicz, CM Havel, MW Peng, P Jacob III… - … , biomarkers & prevention, 2009 - AACR
… A variety of biomarkers have been used to access tobacco exposure in smokers and … ) is
highly tobacco specific and seems to have the longest half-life of all the biomarkers studied thus …