Biomarkers predictive of survival and response to immune checkpoint inhibitors in melanoma

EM Rizk, AM Seffens, MH Trager, MR Moore… - American journal of …, 2020 - Springer
… This review summarizes current prognostic biomarkers and predictive biomarkers for ICIs
in … will respond to immune checkpoint inhibition. Other biomarkers mentioned in this review …

[HTML][HTML] Immune biomarkers of response to immune-checkpoint inhibitors in head and neck squamous cell carcinoma

M Oliva, A Spreafico, M Taberna, L Alemany… - Annals of oncology, 2019 - Elsevier
biomarker is warranted. This review examines the available evidence on emerging immune
predictive biomarkers of response to … use as a predictive immune biomarker in this disease. …

Predictive biomarkers of response to immune checkpoint inhibitors in hepatocellular carcinoma

A Muhammed, A D'Alessio, A Enica… - Expert Review of …, 2022 - Taylor & Francis
… been explored as predictive biomarker of response to PD-1/PD-L1 inhibitors. The phase 2
Keynote-158 study showed a significantly improved response to pembrolizumab in multiple …

Strategies for predicting response to checkpoint inhibitors

R Zappasodi, JD Wolchok, T Merghoub - Current hematologic malignancy …, 2018 - Springer
response. This underscores the need to improve our understanding of the molecular determinants
of response to … Here, we describe available biomarkers of checkpoint blockade activity …

[HTML][HTML] Predictive biomarkers for cancer immunotherapy with immune checkpoint inhibitors

R Bai, Z Lv, D Xu, J Cui - Biomarker research, 2020 - Springer
checkpoint inhibitors (ICIs) therapy has ushered in a new era of anti-tumor therapy, with
sustained responses … and development of predictive biomarkers for the response of ICIs, and …

Tumor mutational burden as a predictive biomarker for response to immune checkpoint inhibitors: a review of current evidence

SJ Klempner, D Fabrizio, S Bane, M Reinhart… - The …, 2020 - academic.oup.com
… established independent predictor of immune checkpoint inhibitor (ICPI) treatment outcome
… ICPIs by response rate and survival. TMB, alongside other genomic biomarkers, may provide …

[HTML][HTML] Immune checkpoint inhibitors in hepatocellular cancer: current understanding on mechanisms of resistance and biomarkers of response to treatment

AE Onuma, H Zhang, H Huang, TM Williams… - Gene …, 2020 - ncbi.nlm.nih.gov
biomarkers of response to ICIs and address future direction on overcoming resistance to
immune checkpoint … Finally, we will describe emerging biomarkers of response to ICIs and …

[HTML][HTML] Biomarkers of response to PD-1/PD-L1 inhibition

SM Vareki, C Garrigós, I Duran - Critical reviews in oncology/hematology, 2017 - Elsevier
… and the interaction of multiple elements is eventually required to define the best biomarkers
of response to checkpoint inhibitors. Ultimately identifying predictive biomarkers requires …

[HTML][HTML] Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer

JA Bridge, JC Lee, A Daud, JW Wells… - Frontiers in …, 2018 - frontiersin.org
… , so to reliable biomarkers of responses to cancer immunotherapy. … for immune-related
biomarkers pertaining to Melanoma, Basal … checkpoint inhibitor therapy biomarker advancements. …

Predictive biomarkers for response to immune checkpoint inhibitors in lung cancer: PD-L1 and beyond

H Uruga, M Mino-Kenudson - Virchows Archiv, 2021 - Springer
… Therefore, other biomarkers have … checkpoint inhibitor (ICI) therapy in general. Of those,
TMB has been extensively studied as an alternative or complementary biomarker for response to …