… Therefore, biomarkers which could detect HCC early with a … This review will aim to provide
an overview of the different biomarkers … and prediction of response to therapeutic intervention. …

… Finally, we will describe emerging biomarkers of response to ICIs and address future … Finally,
we will describe emerging biomarkers of response to ICIs and address future directions on …

… response) may have an increased clinical role in the near future. Furthermore, some serum
biomarkers are … and foreseen future of HCC biomarkers implicated in surveillance, diagnosis, …

… However, there are already indications that biomarkers predictive of a response to PD-1
blockade in HCC may be distinct from those that are relevant in other cancer types. For instance, …

… for regorafenib in colorectal cancer and gastrointestinal … for biomarkers predicting response
to regorafenib treatment in HCC has led to the identification of protein and miRNA biomarker …

… A number of clinical biomarkers to measure the severity of cancer‐related inflammation
are now available, most of which emerge from routine blood parameters including neutrophil, …

… in the majority of liver cancers and the significant … , and biomarker-driven therapies are
currently under evaluation in phase 2/3 clinical trials. Here, we summarize the status on biomarker …

… response to specific therapies [14–16]. Therefore, we should be familiar with well-established …
novel biomarkers for managing HCC. Here, we summarize and update useful biomarkers …

… understanding the biomarkers that predict clinical response to … the key predictive and prognostic
biomarkers investigated in … use of TILs as a biomarker of response to neoadjuvant ICIs in …

… response and survival benefit from immunotherapy have become an area of high unmet
need in HCC. Predictive biomarkers … of predictive biomarkers of response to immune-based …