… towards the search for this reported hypoglycemic activity, a … of the bis-indole alkaloids partly
responsible for this activity: … 'R compounds are devoid of any significant antitumor activity. …

… The aims of the present study were to identify anti-cancer compounds, namely apoptosis
inducers, from Tabernaemontana elegans, and hence to validate its usage in traditional …

… a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, … new
bisindole alkaloid, conophyllinine in addition to the previously known, biologically active bisindole, …

… Anticancer activity of bisindole alkaloids derived from natural sources and synthetic
bisindole hybrids. Archiv der Pharmazie 2020, 353 (9) https://doi.org/10.1002/ardp.202000092 …

… These alkaloids 3 and 5 also exhibited potent anti-cancer activity against lung cancer cell
lines as well as melanoma, renal cell carcinoma, breast, and colon adrenocarcinoma [22,40]. …

… It is noteworthy that only the bisindole alkaloids 1–6 showed inhibitory activities (Table 3).
Among them, ervachinines A (1) and C (3) showed significant inhibitory activity against the five …

… Staurosporine with anticancer activities, kinase inhibitors, re… a structural relationship with
antitumor, antiviral and antidiabetic … The six molecules represent the only bisindole that is now …

Ten vobasinyl-ibogan type bisindole alkaloids, including three new ones, tabercorines A–C (1–3),
and a new natural product, 17-acetyl-tabernaecorymbosine A (4), were isolated from …

… Moreover, among all the bisindole moieties reported in this study, molecules with the cyano
group at R 4 showed the best anticancer activity when there is no group at R 1 , R 2, and R 3 …

… Anticancer activity of bisindole alkaloids derived from natural sources and synthetic
bisindole hybrids. Archiv der Pharmazie 2020, 353 (9) https://doi.org/10.1002/ardp.202000092 …