… bitter compounds by ingestion or breathing. In the present work we addressed the question
whether bitter taste receptors … Here, we show for the first time the expression of TAS2R1 and …

… human taste 2 receptors (… as bitter. In this study, we therefore have systematically investigated
the molecular receptive ranges of bitter taste receptors using 104 natural or synthetic bitter …

… We found that type 2 taste receptors (TAS2Rs), which are activated by bitter-tasting
compounds such as those found in many foods and pharmaceuticals, negatively regulate thyroid-…

… For the receptor TAS2R1 in silico analyses suggest that, either TM I, TM II, TM III, and TM
VII contain positions involved in agonist interaction [52], or, according to another study TM III, …

… This finding indicates that other TAS2Rs aside from TAS2R1, TAS2R4, and TAS2R39
contribute to the bitterness of peptides and supports the existence of further peptide-responsive …

… This hypothesis is supported by the discovery that altered bitter taste perception even …
Bitter taste perception in humans is mediated by 25 functional bitter taste receptors (TAS2R1…

… In summary, we compared the ligand sensitivity of the bitter taste receptors of NWMs. We
found that sensitivity of TAS2Rs varies among species. These results raise the possibility that …

… demonstrated to encode bitter taste receptors referred to as taste 2 receptors, TAS2Rs, or …
A single gene, the TAS2R1 gene, is present on the short arm of chromosome 5. Two loci are …

… In our study, TAS2R1 … of TAS2R1, TAS2R39 was also activated by compound 3 and
compound 8, and TAS2R8 responded to compound 3. A previous study demonstrated that TAS2R1 …

… bitter taste receptor TAS2R46 and are fully functional. Another study by Wölfle showed TAS2R1
… They demonstrated differences in the expression of bitter taste receptors according to sex…