… that 76.3% (45/59) of the bla IMP gene cassettes are located adjacent to Pc promoter of the
class 1 integrons, indicating that the bla IMP genes are readily expressed in most of bacterial …

… an enzyme that is closely related to the IMP-1 metallo-β-lactamase in Europe. Since the …
different from bla IMP found in Japanese isolates. In this case, the host of the bla IMP allele was …

… Molecular screening for bla VIM , bla IMP , and bla SPM-1 was performed by using PCR,
as previously described (29), with primers targeting conserved regions of the MβL genes (Table …

… Since it was found to be an allelic variant (named bla IMP-2 ) ofbla IMP found in Japanese
isolates, we also purified the IMP-2 enzyme and analyzed its kinetic properties with various β-…

… bla IMP or bla VIM showed that 19 isolates (0.9% of the 204 screened) from 16 patients carried
bla IMP … were all carrying the same MBL gene, bla IMP-4 . Further PCR analysis showed …

… the carbapenem-hydrolyzing metallo-β-lactamase gene bla IMP in pathogenic bacteria by …
gene encoding a variant metallo-β-lactamase, designated IMP-3, which differed from IMP-1 by …

… characterized a novel enterobacterial metallo-β-lactamase, IMP-1, … However, in the present
study, the metallo-β-lactamase gene … a potential translocation of the metalloβ-lactamase gene …

… coli OverExpress C43 (DE3) cells (Lucigen, Middleton, WI) were transformed with the pET26b
plasmids carrying bla IMP-1-V67A , bla IMP-1-V67I , and bla IMP-10 via electroporation. …

… IMP -positive GNR have not been clarified. To address these points, we first developed a rapid
and simple method for the detection of the bla IMP … with GNR carrying the bla IMP gene to …

… to screen positive bla VIM-1 , bla VIM-2 and bla IMP-1 control … The VIM and IMP classes of
metallo-β-lactamases include at … the specific detection of bla VIM and bla IMP genes in Gram-…