CSF, blood-brain barrier, and brain drug delivery

WM Pardridge - Expert opinion on drug delivery, 2016 - Taylor & Francis
… (CSF), the blood-brain barrier (BBB), and brain drug delivery, which date back to the
discovery of a barrier between blood and brain over 100 years ago. Misconception 1 is that drug

The blood-brain barrier and brain drug delivery

JM Koziara, PR Lockman, DD Allen… - … of nanoscience and …, 2006 - ingentaconnect.com
… a thorough review of drug delivery to the brain with a particular focus on using drug carriers
such as liposomes and nanoparticles. Challenges in brain drug delivery arise from the …

Drug delivery to brain via the bloodbrain barrier

JM Scherrmann - Vascular pharmacology, 2002 - Elsevier
… to enhance drug delivery across the BBB. … for drug delivery A 603 across bloodbrain
barrier and its functional control IVth International Conference, Cerebral Biology BloodBrain

Blood-brain barrier and new approaches to brain drug delivery.

WM Pardridge, RJ Boado, KL Black… - Western journal of …, 1992 - ncbi.nlm.nih.gov
… from blood. Safe strategies are needed for drug delivery through the brain capillary wall,
which makes up the blood-brain barrier in vivo. Two of these strategies are reviewed, as are …

[HTML][HTML] Nanoparticle-mediated brain drug delivery: Overcoming bloodbrain barrier to treat neurodegenerative diseases

C Saraiva, C Praça, R Ferreira, T Santos… - Journal of controlled …, 2016 - Elsevier
… to drug delivery into the brain. The use … brain vasculature, may enhance drug transport
through the BBB in neurodegenerative/ischemic disorders and target relevant regions in the brain

Drug delivery to the brain in Alzheimer's disease: Consideration of the bloodbrain barrier

WA Banks - Advanced drug delivery reviews, 2012 - Elsevier
… Drugs targeted to the CNS must negotiate the bloodbrain barrier (BBB). This review will
examine various aspects of the BBB that are relevant to drug delivery. This includes strategies …

Brain drug delivery and bloodbrain barrier transport

WM Pardridge - Drug Delivery, 1993 - Taylor & Francis
Brain drug development requires advances in both brain drug discovery and brain drug
delivery. Owing to the presence of the blood-brain barrier (BBB), only small lipid-soluble drugs in …

From bloodbrain barrier to bloodbrain interface: new opportunities for CNS drug delivery

WA Banks - Nature reviews Drug discovery, 2016 - nature.com
… complicates CNS drug delivery, but also provides many unique opportunities for drug delivery.
… Finally, I discuss future directions for CNS drug delivery that combine new and classical …

Drug delivery to the brain across the bloodbrain barrier using nanomaterials

YH Tsou, XQ Zhang, H Zhu, S Syed, X Xu - Small, 2017 - Wiley Online Library
… for brain drug delivery are discussed. The properties of the nanocarriers and the factors that
affect drug delivery … of nanoformulations and nonconventional drug delivery strategies are …

Overcoming the bloodbrain barrier. challenges and tricks for CNS drug delivery

LA Bors, F Erdő - Scientia Pharmaceutica, 2019 - mdpi.com
… the various options to help drug delivery to the brain, to open the BBB or to make some
tricks the overcome the barrier. To realize the theory behind the drug delivery concept, it is …