The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery
DR Groothuis - Neuro-oncology, 2000 - academic.oup.com
… of most local delivery … blood-brain barrier are presented in this review, and special attention
is given to convection-enhanced delivery, which has particular promise for the local delivery …
is given to convection-enhanced delivery, which has particular promise for the local delivery …
Advances in nanocarriers enabled brain targeted drug delivery across blood brain barrier
G Sharma, AR Sharma, SS Lee, M Bhattacharya… - International journal of …, 2019 - Elsevier
… are also being explored for their drug delivery potential against BBB. Although, studies … in
drug delivery across BBB, but still, progress in the development of any functional drug delivery …
drug delivery across BBB, but still, progress in the development of any functional drug delivery …
Drug delivery across the blood-brain barrier
Y Chen, G Dalwadi, HAE Benson - Current drug delivery, 2004 - ingentaconnect.com
… In addition to peptidomimetic MAbs as brain drug delivery vectors, approaches using viral
vectors have also been explored, but almost exclusively for gene therapy of the brain. Gene …
vectors have also been explored, but almost exclusively for gene therapy of the brain. Gene …
Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting
CV Pardeshi, VS Belgamwar - Expert opinion on drug delivery, 2013 - Taylor & Francis
… Clusters of authors have reviewed diverse aspects relevant to nasal drug delivery systems
but there are only a few reports highlighting the crucial aspects of nose to brain drug delivery …
but there are only a few reports highlighting the crucial aspects of nose to brain drug delivery …
[HTML][HTML] The blood–brain barrier: structure, regulation, and drug delivery
… science and nanotechnology in brain-targeted drug delivery. Brain disorder therapy utilizing
… In the light of excellent performance of BBB crossing strategies for enhanced drug delivery, …
… In the light of excellent performance of BBB crossing strategies for enhanced drug delivery, …
Blood–brain barrier structure and function and the challenges for CNS drug delivery
NJ Abbott - Journal of inherited metabolic disease, 2013 - Springer
… and transport across the brain endothelium forming the blood–brain barrier. a … brain
endothelium has physical, transport, enzymatic and immunological barrier functions. Drug delivery to …
endothelium has physical, transport, enzymatic and immunological barrier functions. Drug delivery to …
Crossing the blood–brain barrier: recent advances in drug delivery to the brain
CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …
[HTML][HTML] Current strategies for brain drug delivery
X Dong - Theranostics, 2018 - ncbi.nlm.nih.gov
… Current non-nanoparticle strategies are also reviewed, such as delivery of drugs through …
brain drug uptake. Finally, one particular area that is often neglected in brain drug delivery is …
brain drug uptake. Finally, one particular area that is often neglected in brain drug delivery is …
The blood-brain barrier: Physiology and strategies for drug delivery
The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper, reflecting
the unique requirements of the brain. In this review, following a brief historical overview of …
the unique requirements of the brain. In this review, following a brief historical overview of …
Drug delivery to the brain
WM Pardridge - Journal of Cerebral Blood Flow & …, 1997 - journals.sagepub.com
… Brain drug delivery plays an essential role in modern drug development for the central
nervous system (CNS). In the past, the pathway from new drug discovery to drug development for …
nervous system (CNS). In the past, the pathway from new drug discovery to drug development for …