The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery

DR Groothuis - Neuro-oncology, 2000 - academic.oup.com
… of most local deliveryblood-brain barrier are presented in this review, and special attention
is given to convection-enhanced delivery, which has particular promise for the local delivery

Advances in nanocarriers enabled brain targeted drug delivery across blood brain barrier

G Sharma, AR Sharma, SS Lee, M Bhattacharya… - International journal of …, 2019 - Elsevier
… are also being explored for their drug delivery potential against BBB. Although, studies … in
drug delivery across BBB, but still, progress in the development of any functional drug delivery

Drug delivery across the blood-brain barrier

Y Chen, G Dalwadi, HAE Benson - Current drug delivery, 2004 - ingentaconnect.com
… In addition to peptidomimetic MAbs as brain drug delivery vectors, approaches using viral
vectors have also been explored, but almost exclusively for gene therapy of the brain. Gene …

Direct nose to brain drug delivery via integrated nerve pathways bypassing the bloodbrain barrier: an excellent platform for brain targeting

CV Pardeshi, VS Belgamwar - Expert opinion on drug delivery, 2013 - Taylor & Francis
… Clusters of authors have reviewed diverse aspects relevant to nasal drug delivery systems
but there are only a few reports highlighting the crucial aspects of nose to brain drug delivery

[HTML][HTML] The bloodbrain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
… science and nanotechnology in brain-targeted drug delivery. Brain disorder therapy utilizing
… In the light of excellent performance of BBB crossing strategies for enhanced drug delivery, …

Bloodbrain barrier structure and function and the challenges for CNS drug delivery

NJ Abbott - Journal of inherited metabolic disease, 2013 - Springer
… and transport across the brain endothelium forming the bloodbrain barrier. a … brain
endothelium has physical, transport, enzymatic and immunological barrier functions. Drug delivery to …

Crossing the bloodbrain barrier: recent advances in drug delivery to the brain

MM Patel, BM Patel - CNS drugs, 2017 - Springer
CNS disorders are on the rise despite advancements in our understanding of their
pathophysiological mechanisms. A major hurdle to the treatment of these disorders is the …

[HTML][HTML] Current strategies for brain drug delivery

X Dong - Theranostics, 2018 - ncbi.nlm.nih.gov
… Current non-nanoparticle strategies are also reviewed, such as delivery of drugs through …
brain drug uptake. Finally, one particular area that is often neglected in brain drug delivery is …

The blood-brain barrier: Physiology and strategies for drug delivery

R Pandit, L Chen, J Götz - Advanced drug delivery reviews, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper, reflecting
the unique requirements of the brain. In this review, following a brief historical overview of …

Drug delivery to the brain

WM Pardridge - Journal of Cerebral Blood Flow & …, 1997 - journals.sagepub.com
Brain drug delivery plays an essential role in modern drug development for the central
nervous system (CNS). In the past, the pathway from new drug discovery to drug development for …