过去一年中添加的文章,按日期排序

Development of a targeted method for DNA adductome and its application as sensitive biomarkers of ambient air pollution exposure

R Xu, Y Zhang, Y Gao, S Jia, S Choi, Y Xu… - Journal of Hazardous …, 2024 - Elsevier
8 天前 - DNA adducts in peripheral blood cells from pregnant women in Shanxi and Beijing.
Up to 23 DNA adducts … to detect multiple DNA adducts in peripheral blood leukocytes from …

BORON-BASED THERANOSTICS AND PRODRUGS: DESIGN, SYNTHESIS, MECHANISM AND BIOLOGICAL INVESTIGATION

E Saxon - 2024 - dc.uwm.edu
22 天前 - … matrix, while oxidative deboronation only occurs in the presence of cancer cells. …
along with DNA-alkylating capability to produce cytotoxic interstrand-crosslinked (ICL) adducts. …

Detection of γ-OHPdG in circulating tumor cells of patients with hepatocellular carcinoma as a potential prognostic biomarker of recurrence

M Aggarwal, M Kuo, Z Zhu, S Gould, K Zhang… - Gastro Hep …, 2024 - Elsevier
71 天前 - … γ-OHPdG is a background DNA adduct in the cells and tissues of rodents and humans
15. It … knowledge, the method descried here is the first to detect a specific DNA adduct in …

[PDF][PDF] Therapeutic effect of Bacopa monnieri on Aflatoxin B1-induced oxidative damage in rats

A Rathour, SS Gupte, S Shrivastava, S Shukla - floraandfona.org.in
76 天前 - … This extremely reactive metabolite forms adducts with DNA guanine, causing a
harmful impact. AFB1 is very toxic and carcinogenic mycotoxin to the liver. The mechanism of …

Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food

G Eisenbrand, A Buettner, P Diel, B Epe, P Först… - Archives of …, 2024 - Springer
91 天前 - … (NDMA) in human blood and on DNA adduct levels in blood cells. Further NOC have
not been … These findings require consolidation by refined toxicokinetics and DNA adduct

Particulate polycyclic aromatic hydrocarbons and metals, DNA methylation and DNA methyltransferase among middle-school students in China

W Gu, T Wang, Y Lin, Y Wang, Y Chen, Y Dai… - Science of The Total …, 2024 - Elsevier
96 天前 - … White blood cells were detected by the automatic biochemistry analyzer (ADVIA
2400, … Our results showed that BPDE-albumin adduct and urinary Cd significantly decrease in …

Detection of γ-OHPdG as a hepatocellular carcinoma recurrence biomarker by CTCs and LC-MS/MS

M Kuo, MO Aktop, E Ghabi, MA Ouf, M Carder… - Cancer Research, 2024 - AACR
104 天前 - … We previously showed that hepatic γ-hydroxy-1, N 2 -propano-2′-deoxyguanosine
(γ-OHPdG), a DNA adduct derived from lipid peroxidation, increased during …

Reducing DNA Damage Associated with Endogenous Genotoxic Stress in Hematopoietic Stem Cells

B Singh, CS Salinas, MA Hossain, C Millington, K Patel… - Blood, 2023 - Elsevier
219 天前 - cells as it is produced as a byproduct during normal cellular metabolism such as
histone, RNA and DNA … therefore accumulate formaldehyde adducts in DNA that require the FA …

DNA damage response after treatment of cycling and quiescent cord blood hematopoietic stem cells with distinct genotoxic noxae

F Becker, M Ouzin, S Liedtke, K Raba, G Kogler - Stem Cells, 2024 - academic.oup.com
233 天前 - … To analyze different mechanisms of DNA damage induction in cellsDNA adducts
resulting in DNA double breaks during DNA replication and persistent mutations. Cycling cells

Aldehyde dehydrogenase 2 gene rs671 G> A polymorphism is associated with an increased risk of digestive tract cancer

Y Yang, Q Liang, Y Chen, Y Cao… - Journal of …, 2023 - journals.sagepub.com
254 天前 - … One study showed that accumulated acetaldehyde in cells can form acetaldehyde-DNA
adducts, resulting in genetic abnormalities. Genetic damage of this nature can promote …