Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers.
JL Fang, CE Vaca - Carcinogenesis, 1997 - academic.oup.com
… Aa in peripheral blood than in men have been detected in women after … DNA adduct levels
of Aa were not observed within each cell type in our study. It should ethanol and acetaldehyde …
of Aa were not observed within each cell type in our study. It should ethanol and acetaldehyde …
DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis
PJ Brooks, JA Theruvathu - Alcohol, 2005 - Elsevier
… in white blood cell DNA obtained from human alcohol abusers and control subjects (Fang
& Vaca, 1997). They found that the levels of lesion in white blood cell DNA obtained from the …
& Vaca, 1997). They found that the levels of lesion in white blood cell DNA obtained from the …
Identification of DNA adducts of acetaldehyde
M Wang, EJ McIntee, G Cheng, Y Shi… - Chemical research in …, 2000 - ACS Publications
… with DNA. In this study, we identified three new types of stable acetaldehyde DNA adducts,
… N 2 -Ethyl-dG has been detected in the DNA of peripheral white blood cells of alcohol …
… N 2 -Ethyl-dG has been detected in the DNA of peripheral white blood cells of alcohol …
Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis
PJ Brooks, S Zakhari - Environmental and molecular …, 2014 - Wiley Online Library
… and acetaldehyde metabolism, we focus on the different acetaldehyde-DNA adducts, including
a critical assessment of the evidence supporting a role for acetaldehyde-DNA adducts in …
a critical assessment of the evidence supporting a role for acetaldehyde-DNA adducts in …
Formation of acetaldehyde-derived DNA adducts due to alcohol exposure
HS Yu, T Oyama, T Isse, K Kitagawa, M Tanaka… - Chemico-biological …, 2010 - Elsevier
… These studies support that numerous DNA adducts are highly related to … of DNA adducts
in alcohol-related cancer. Although the carcinogenicity of acetaldehyde-derived DNA adducts …
in alcohol-related cancer. Although the carcinogenicity of acetaldehyde-derived DNA adducts …
Analysis of DNA adducts of acetaldehyde by liquid chromatography–mass spectrometry
S Inagaki, Y Esaka, Y Deyashiki, M Sako… - … of Chromatography A, 2003 - Elsevier
… When gas chromatography (GC), liquid chromatography (LC) or capillary electrophoresis
is used in conjunction with MS, we can detect many kinds of DNA adducts accurately with …
is used in conjunction with MS, we can detect many kinds of DNA adducts accurately with …
Stability of acetaldehyde-derived DNA adduct in vitro
K Hori, S Miyamoto, Y Yukawa, M Muto, T Chiba… - Biochemical and …, 2012 - Elsevier
… DNA adduct was analyzed by liquid chromatography–tandem mass spectrometry. ► The
half-life of DNA adducts was estimated as 35 h in vitro in HL60 cells. ► Acetaldehyde …
half-life of DNA adducts was estimated as 35 h in vitro in HL60 cells. ► Acetaldehyde …
Formation of DNA adducts in human buccal epithelial cells exposed to acetaldehyde and methylglyoxal in vitro
CE Vaca, JA Nilsson, JL Fang, RC Grafström - Chemico-biological …, 1998 - Elsevier
… was demonstrated in cultured human epithelial cells. Furthermore, these DNA adducts
were formed in a dose-dependent manner at aldehyde concentrations that were relatively non-…
were formed in a dose-dependent manner at aldehyde concentrations that were relatively non-…
Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N2-Ethyldeoxyguanosine
M Wang, N Yu, L Chen, PW Villalta… - Chemical research in …, 2006 - ACS Publications
… Quantitation of acetaldehyde−DNA adducts in human tissues … DNA adduct of acetaldehyde
formed upon reaction with DNA … such as white blood cells and exfoliated oral cells, but on the …
formed upon reaction with DNA … such as white blood cells and exfoliated oral cells, but on the …
Quantitation of an acetaldehyde adduct in human leukocyte DNA and the effect of smoking cessation
L Chen, M Wang, PW Villalta, X Luo… - Chemical research in …, 2007 - ACS Publications
… The role of acetaldehyde DNA adducts in human cancer related to … for analysis of the major
DNA adduct of acetaldehyde, N 2 -… Further studies using DNA from individual white blood cell …
DNA adduct of acetaldehyde, N 2 -… Further studies using DNA from individual white blood cell …
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