Single-cell RNA sequencing to disentangle the blood system

J Acosta, D Ssozi, P van Galen - Arteriosclerosis, thrombosis, and …, 2021 - Am Heart Assoc
… new insights into blood cell differentiation generated by single-cell RNA sequencing, summarize
… that are leading the way to understand hematopoiesis at the resolution of single cells. …

Single cell RNA-seq analysis of human red cells

V Jain, WH Yang, J Wu, JD Roback… - Frontiers in …, 2022 - frontiersin.org
… Human red blood cells (RBCs), or erythrocytes, are the most abundant blood cells
responsible for gas exchange. RBC diseases affect hundreds of millions of people and impose …

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

SL Smith, PR Kennedy, KB Stacey… - Blood …, 2020 - ashpublications.org
… Human natural killer (NK) cells in peripheral blood perform many … -cell RNA sequencing
of NK cells, comparing gene expression in unstimulated and interleukin (IL)-2–activated cells

Single-cell RNA sequencing identifies novel cell types in Drosophila blood

Y Fu, X Huang, P Zhang, J van de Leemput… - Journal of Genetics and …, 2020 - Elsevier
cells and lamellocytes. To better understand the complexity of fly blood system, we used
single-cell RNA sequencing … for Drosophila circulating blood cells. In addition to the known …

RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson's disease

DW Craig, E Hutchins, I Violich, E Alsop, JR Gibbs… - Nature Aging, 2021 - nature.com
… -blood-based RNA sequencing (RNA-seq) for integration with other clinical and molecular
readouts (including whole-genome sequencing … changes associated with blood cell types and …

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

AC Villani, R Satija, G Reynolds, S Sarkizova… - Science, 2017 - science.org
… -cell RNA sequencing (RNA-seq) of ~2400 cells, we identified six human DCs and four
monocyte subtypes in human blood… (pDCs) but potently activates T cells, thus redefining pDCs; a …

Can single cell RNA sequencing reshape the clinical biochemistry of hematology: New clusters of circulating blood cells

H Fang, Y Zeng, L Zhang, C Chen… - Clinical and …, 2021 - Wiley Online Library
… opportunities of scRNA-seq development. Can single-cell RNA sequencing (scRNA-seq) act
as … Can the comprehensive information obtained from scRNA-seq assist in clinical decision-…

Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis

XC Zhao, SH Yang, YQ Yan, X Zhang, L Zhang… - BMC Medical …, 2018 - Springer
… In this study, we use RNA sequencing technology, bioinformatics analysis and Western
blotting to identify key genes from peripheral blood cells of military pilots with hypertension. …

New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNASeq

TD Otto, D Wilinski, S Assefa, TM Keane… - Molecular …, 2010 - Wiley Online Library
… Our RNA-Seq results correlate well with DNA microarray analysis … of the parasite's red blood
cell-stage transcriptome. … In this study, we applied RNA-Seq to seven time points from the …

Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

EI Athanasiadis, JG Botthof, H Andres, L Ferreira… - Nature …, 2017 - nature.com
… of single-cell gene expression in adult zebrafish blood cells and computationally … -cell
RNA-seq to reveal the cellular properties and gene expression of a large number of blood cells