… metabolic changes associated with normal aging. We simultaneously measured both the
magnitude of the blood oxygenation level dependent (BOLD) and cerebral blood flow (CBF) …

… the oxygen 15 continuous inhalation method, we examined the changes in cerebral … rate
of oxygen, blood flow, blood volume, and oxygen extraction fraction as a function of age in 25 …

… using the improved oxygen-15 … (oxygen extraction fraction) and CBV (cerebral blood volume)
to obtain normal values for comparison with our patient studies and to study the effect of age…

… selectively affects gray matter and spares white matter, then our findings, as a result of this
averaging effect, would underestimate true age-related changes in gray matter. Conversely, …

Purpose: To prospectively investigate age-related changes in muscle reperfusion by using
blood oxygen level–dependent (BOLD) magnetic resonance (MR) imaging of the calf in …

… favourable conditions of tissue oxygenation. We conclude that the human RBC aging process
is not only a suitable model to study the cellular and tissutal aging mechanisms, but may …

… age [44], can confound findings of aging effects on CBF. One study reported that cerebral
venous oxygenation … [33], indicating that the oxygen supply/demand equilibrium undergoes a …

… In healthy volunteers, BOLD-signal aging effects and … elderly healthy volunteers to assess
age-related changes and uses a … and evaluate potential aging effects in simultaneous calf and …

… To illustrate the overall effects of preprocessing on our age-based variability effects, we first
calculated average temporal signal variance across fixation scans within one run (run 1). To …

… geometry and control such that the dynamics of muscular blood flow ( Q ) and O 2 delivery (
… blood–tissue O 2 transfer compromised. This investigation determined the effects of aging on …