The genetic architecture of blood pressure variation

PB Munroe, T Johnson, MJ Caulfield - Current Cardiovascular Risk …, 2009 - Springer
… sizes in genes causing monogenic disorders have also been found, suggesting blood
pressure heritability may be explained in part by a combination of both common and rare genetic

Genetic basis of blood pressure and hypertension

S Padmanabhan, C Newton-Cheh, AF Dominiczak - Trends in Genetics, 2012 - cell.com
Variation in extracellular fluid volume, the contractile state of the heart and vascular tone
contribute to variation in BP level. Other determinants of BP include age, weight, ethnicity and …

Genetic variations related to hypertension: a review

MOM Tanira, KA Al Balushi - Journal of human hypertension, 2005 - nature.com
… to summarize present known genetic variations that may be … genetic variations to improve
management of hypertension. … and blood pressure, or looking directly for gene variations

The genetics of blood pressure and hypertension: the role of rare variation

PA Doris - Cardiovascular therapeutics, 2011 - Wiley Online Library
… that the genetic architecture of blood pressure regulation in the … occurring genetic variation
in a discrete set of blood pressure-… genetic diversity and population-specific genetic variation. …

Molecular genetics of human blood pressure variation

RP Lifton - Science, 1996 - science.org
… It seems likely that single gene disorders of blood pressure regulation will cumulatively
explain only a small fraction of the total genetic variation in blood pressure in the population, …

Common genetic variations in the vitamin D pathway in relation to blood pressure

L Wang, A Chu, JE Buring, PM Ridker… - American journal of …, 2014 - academic.oup.com
… Vitamin D is involved in blood pressure (BP) regulation. Genetic variations may influence …
ancestry and in the International Consortium of Blood Pressure (ICBP) with genome-wide meta-…

[HTML][HTML] The association of genetic variations with sensitivity of blood pressure to dietary salt: A narrative literature review

S Doaei, M Gholamalizadeh - ARYA atherosclerosis, 2014 - ncbi.nlm.nih.gov
… Several genetic variations have been identified as … gene variations could influence the
level of nutrients requirements.8 On the other hand, intake of some nutrients could alter the gene

Association of genetic variation with blood pressure traits among East Africans

J Kayima, J Liang, Y Natanzon, J Nankabirwa… - … genetics, 2017 - Wiley Online Library
Genetic variation may play explain some of the disparity in prevalence and control of … ,
there have been very few studies to characterize genetic variation of blood pressure traits. …

Association between genetic variation in blood pressure and increased lifetime risk of peripheral artery disease

MG Levin, D Klarin, VM Walker, D Gill… - … , and vascular biology, 2021 - Am Heart Assoc
… the effect of blood pressure (BP) traits and BP-lowering medications (via genetic proxies) on
… The effects of antihypertensive medications were estimated using genetic instruments. SBP-…

[HTML][HTML] β-2 adrenoceptor genetic variation is associated with genetic predisposition to essential hypertension: The Bergen Blood Pressure Study

B Timmermann, R Mo, FC Luft, E Gerdts, A Busjahn… - Kidney international, 1998 - Elsevier
… predisposition to essential hypertension: The Bergen Blood Pressure Study. We tested the
hypothesis that genetic variation in the β-2 adrenoceptor gene is associated with a genetic