… This major milestone in malaria vaccine development history has proved that an efficacious
malaria vaccine is achievable. However, a more efficacious second-generation vaccine is …

… , should help to improve our ability to assess malaria vaccines targeting the blood stages,
in Phase-IIa trials. Two vaccines against the blood stages, FMP1 and AMA1-C1 in Alhydrogel, …

… Blood-stage malaria vaccines are intended to prevent clinical disease. The malaria vaccine
FMP2.1/AS02 A , a recombinant protein based on apical membrane antigen 1 (AMA1) from …

… of malaria. These data suggest not only that there are many more potential antigen candidates
for the malaria vaccine development pipeline but also that effective vaccination may be …

… The use of asexual blood-stage proteins as malaria vaccines is strongly supported by …
blood-stage antigens is based on their ability to interfere with the pathogenesis of clinical malaria …

… We arrayed several recombinant blood stage malaria proteins (19)(20)(21)(22)(23)(24)(25),
all of which are prime vaccine candidates, to form the substrate of an antibody-capture …

… blood-stage parasite densities and disease severity. Pre-erythrocytic and blood-stage malaria
vaccines … combined into a multi-stage malaria vaccine to be optimally safe and effective. …

… preerythrocytic stage to prevent infection, at the blood stage to … or the sexual and mosquito
stages to prevent transmission. Here… of malaria vaccines that target the blood stage of malaria …

… They are largely ignored in most blood-stage malaria vaccine development strategies. Here…
the development of a blood-stage malaria vaccine. Key words: Plasmodium, vaccine, cell-…

… results from PEV3A vaccinated volunteers. … blood of all (n = 24) PEV3A vaccinated volunteers,
and in only 2/6 controls (p = 0.001). We describe evidence of vaccine-induced blood stage …