… canonical signaling downstream of the BMP type IA receptor is a key mediator of quiescence
… that BMPR-IA is essential in regulating the equilibrium between stem cell proliferation and …

… Neural stem cells (NSCs) generate neurons and glial cells throughout embryonic and
postnatal brain development. The role of S-palmitoylation (also referred to as S-acylation), a …

… Thereafter, the neural stem cell marker (Nestin) and the specific marker in early stage of
neurons (βIII-tubulin) were detected using qRT-PCR. It was shown that the expression levels of …

… the three BMPRs (BMPRIa, BMPRIb, and … , BMPRIa and BMPRIb have different expression
patterns in the mammalian nervous system. After gastrulation BMPRIa is expressed in neural …

… This model came out of the observations that activation of BMPR-IA by BMPs induced
dorsal identity and proliferation in both transgenic mice and in cultured stem cells. BMPR-IA …

… Replicating these findings in transgenic mouse models allowing selective ablation of these
receptors is crucial to further clarify specific temporal functions of BMPRIA/B during neuronal …

… BMPs promote survival of neuronal-committed type A cells, which express both BMPRIA and
BMPRIB, whereas they have no survival effect on BMPRIA + BMPRIB − type B/C cells. This …

… (+)-Cholesten-3-one significantly increases the expression of BMPR IB, but not BMPR IA or
BMPR II; p-Smad1/5/8 positive nuclei and expression of p-Smad1/5/8 were detected in NSCs …

… the neuronal fate commitment of the stem cell progeny. To … adult rat hippocampal neural
stem and progenitor cells (AH-… undergoing differentiation towards the neuronal lineage. In vitro, …

… , BMPR-IA and BMPR-IB, in neural precursor cells in vitro and in vivo. Neural precursor cells
always expressBmpr-1a, but Bmpr-… and fate of dorsal precursor cells from neural stem cells. …