Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus
… canonical signaling downstream of the BMP type IA receptor is a key mediator of quiescence
… that BMPR-IA is essential in regulating the equilibrium between stem cell proliferation and …
… that BMPR-IA is essential in regulating the equilibrium between stem cell proliferation and …
Palmitoylation of BMPR1a regulates neural stem cell fate
T Wegleiter, K Buthey… - Proceedings of the …, 2019 - National Acad Sciences
… Neural stem cells (NSCs) generate neurons and glial cells throughout embryonic and
postnatal brain development. The role of S-palmitoylation (also referred to as S-acylation), a …
postnatal brain development. The role of S-palmitoylation (also referred to as S-acylation), a …
Soft matrix combined with BMPR inhibition regulates neurogenic differentiation of human umbilical cord mesenchymal stem cells
Y Sun, Z Xu, M Wang, S Lv, H Wu, G Chi… - … in Bioengineering and …, 2020 - frontiersin.org
… Thereafter, the neural stem cell marker (Nestin) and the specific marker in early stage of
neurons (βIII-tubulin) were detected using qRT-PCR. It was shown that the expression levels of …
neurons (βIII-tubulin) were detected using qRT-PCR. It was shown that the expression levels of …
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation
AM Bond, OG Bhalala… - Developmental …, 2012 - Wiley Online Library
… the three BMPRs (BMPRIa, BMPRIb, and … , BMPRIa and BMPRIb have different expression
patterns in the mammalian nervous system. After gastrulation BMPRIa is expressed in neural …
patterns in the mammalian nervous system. After gastrulation BMPRIa is expressed in neural …
The control of neural stem cells by morphogenic signals
DM Panchision, RDG McKay - Current opinion in genetics & development, 2002 - Elsevier
… This model came out of the observations that activation of BMPR-IA by BMPs induced
dorsal identity and proliferation in both transgenic mice and in cultured stem cells. BMPR-IA …
dorsal identity and proliferation in both transgenic mice and in cultured stem cells. BMPR-IA …
Bone morphogenetic protein 4 signalling in neural stem and progenitor cells during development and after injury
… Replicating these findings in transgenic mouse models allowing selective ablation of these
receptors is crucial to further clarify specific temporal functions of BMPRIA/B during neuronal …
receptors is crucial to further clarify specific temporal functions of BMPRIA/B during neuronal …
Concise review: bone morphogenetic protein pleiotropism in neural stem cells and their derivatives—alternative pathways, convergent signals
HL Chen, DM Panchision - Stem cells, 2007 - academic.oup.com
… BMPs promote survival of neuronal-committed type A cells, which express both BMPRIA and
BMPRIB, whereas they have no survival effect on BMPRIA + BMPRIB − type B/C cells. This …
BMPRIB, whereas they have no survival effect on BMPRIA + BMPRIB − type B/C cells. This …
(+)-Cholesten-3-one induces differentiation of neural stem cells into dopaminergic neurons through BMP signaling
DF Chen, LJ Meng, SH Du, HL Zhang, H Li… - Neuroscience …, 2010 - Elsevier
… (+)-Cholesten-3-one significantly increases the expression of BMPR IB, but not BMPR IA or
BMPR II; p-Smad1/5/8 positive nuclei and expression of p-Smad1/5/8 were detected in NSCs …
BMPR II; p-Smad1/5/8 positive nuclei and expression of p-Smad1/5/8 were detected in NSCs …
BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells
T Armenteros, Z Andreu, R Hortigüela, DC Lie… - Scientific Reports, 2018 - nature.com
… the neuronal fate commitment of the stem cell progeny. To … adult rat hippocampal neural
stem and progenitor cells (AH-… undergoing differentiation towards the neuronal lineage. In vitro, …
stem and progenitor cells (AH-… undergoing differentiation towards the neuronal lineage. In vitro, …
Sequential actions of BMP receptors control neural precursor cell production and fate
DM Panchision, JM Pickel, L Studer… - Genes & …, 2001 - genesdev.cshlp.org
… , BMPR-IA and BMPR-IB, in neural precursor cells in vitro and in vivo. Neural precursor cells
always expressBmpr-1a, but Bmpr-… and fate of dorsal precursor cells from neural stem cells. …
always expressBmpr-1a, but Bmpr-… and fate of dorsal precursor cells from neural stem cells. …
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