[HTML][HTML] Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and …

K Boonyawat, F Caron, A Li… - Journal of Thrombosis …, 2017 - Elsevier
… DOAC)‐treated patients about safety and efficacy in extremes of body weight. The aims
of this systematic review were to investigate the association of body weight and patient‐important …

Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: a meta-analysis of …

MND Di Minno, R Lupoli, A Di Minno… - Annals of …, 2015 - Taylor & Francis
… on the safety and efficacy of these new drugs in patients with extreme body weights, and …
evaluate the effect of extreme body weight (BW) on safety and efficacy of DOACs using data …

Lifestyle and pharmacological approaches to weight loss: efficacy and safety

GA Bray - The Journal of Clinical Endocrinology & Metabolism, 2008 - academic.oup.com
… decrease of 4.0 kg in body weight in the group participating in … each decrease of 1 kg in body
weight there was a decrease of … body weight was stable or body weight was still declining. If …

Efficacy and safety of P2Y12 inhibitors according to diabetes, age, gender, body mass index and body weight: systematic review and meta-analyses of randomized …

F Zaccardi, D Pitocco, P Willeit, JA Laukkanen - Atherosclerosis, 2015 - Elsevier
… The efficacy of antiplatelet drugs may differ in specific patient subgroups. We aimed to assess
the efficacy and safety … to diabetes status, age, gender, body mass index, and body weight. …

Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials

R Christensen, PK Kristensen, EM Bartels, H Bliddal… - The Lancet, 2007 - thelancet.com
… for effective and safe anti-obesity agents that can produce and maintain weight loss and …
trials to assess the efficacy and safety of the newly approved anti-obesity agent rimonabant. …

Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: rationale for dosing recommendations

M Lebwohl, N Yeilding, P Szapary, Y Wang, S Li… - Journal of the American …, 2010 - Elsevier
body weight, a prespecified analysis of efficacy (at least 75% improvement from baseline
in PASI score [PASI 75] at week 28) by 10-kg increments was presented for data pooled from …

Efficacy and safety of beloranib for weight loss in obese adults: a randomized controlled trial

DD Kim, J Krishnarajah, S Lillioja… - Diabetes, Obesity …, 2015 - Wiley Online Library
body weight from baseline to the end of the study (weeks 12–13) in all beloranib treatment
groups (Figure 1). The reduction in body weight … in mean and percent body weight was dose-…

Efficacy, safety, and exposure of apixaban in patients with high body weight or obesity and venous thromboembolism: insights from AMPLIFY

AT Cohen, S Pan, W Byon, BS Ilyas, T Taylor… - Advances in Therapy, 2021 - Springer
… However, the efficacy and safety of apixaban in patients with body weight ≥ 120 kg and …
efficacy, safety, and exposure of apixaban for the treatment of VTE in patients with a body weight

Efficacy and safety of apixaban versus warfarin in patients with atrial fibrillation and extremes in body weight: insights from the ARISTOTLE trial

SH Hohnloser, M Fudim, JH Alexander, DM Wojdyla… - Circulation, 2019 - Am Heart Assoc
… ) with known baseline body weight at randomization were … to body weight: 1985 (10.9%)
patients were in the low-weight group (≤60 kg), 15 172 (83.6%) were in the midrange weight

Long-term efficacy and safety of anti-obesity treatment: where do we stand?

YJ Tak, SY Lee - Current obesity reports, 2021 - Springer
… of phentermine/topiramate ER for 1 year had a total body weight loss of 7.8% and 9.8%,
respectively, as compared to the weight loss of 1.2% in patients administered with placebo. Thus…