Osteoblast apoptosis and bone turnover

JM Hock, V Krishnan, JE Onyia… - Journal of Bone and …, 2001 - academic.oup.com
… and controversies in apoptosis research and then considers specific examples of osteoblast
apoptosis pertinent to skeletal development and to the regulation of bone turnover. In …

Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines

RL Jilka, RS Weinstein, T Bellido… - Journal of bone and …, 1998 - academic.oup.com
osteoblasts die by apoptosis and that growth factors and cytokines produced in the bone
We report that murine osteoblastic MC3T3‐E1 cells underwent apoptosis following removal of …

[HTML][HTML] Osteocyte and osteoblast apoptosis and excessive bone deposition accompany failure of collagenase cleavage of collagen

W Zhao, MH Byrne, Y Wang… - The Journal of clinical …, 2000 - Am Soc Clin Investig
… Thus, the failure of collagenase to cleave type I collagen in the Col1a1 r/r mice was
associated with increased osteoblast and osteocyte apoptosis, yet increased bone deposition. …

Age-related bone loss: old bone, new facts

GK Chan, G Duque - Gerontology, 2002 - karger.com
… , any intervention directed at inhibiting this phenomenon would be effective in stemming
bone loss. It is still unclear which are the key factors associated with osteoblast apoptosis. Most …

Apoptosis in bone cells

BF Boyce, L Xing, RL Jilka, T Bellido… - Principles of bone …, 2002 - Elsevier
… joint disease, and the bone loss that results from sex steroid … The decrease in osteoblast
number and bone formation rate … of osteoblast apoptosis observed in murine vertebral bone

Regulation of apoptosis in osteoclasts and osteoblastic cells

L Xing, BF Boyce - Biochemical and biophysical research communications, 2005 - Elsevier
… of these on survival of osteoclasts, osteoblasts, and osteocytes. … of bone cell apoptosis will
enhance our knowledge of bone … osteoclast apoptosis in general leads to increased bone loss

Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss

H He, R Liu, T Desta, C Leone, LC Gerstenfeld… - …, 2004 - academic.oup.com
… factors that regulate osteoblast differentiation. We found that after bacterial insult apoptosis
of bone-lining cells was induced. Diabetes had a profound effect on apoptosis of bone-lining …

Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation

AM Mastro, CV Gay, DR Welch… - Journal of cellular …, 2004 - Wiley Online Library
… for initiation of osteoblast apoptosis both in the normal remodeling process and in disease
states. At this time we do not know which contribute to bone loss by osteolytic breast cancer …

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss

JI Aguirre, LI Plotkin, SA Stewart… - Journal of bone and …, 2006 - academic.oup.com
… of apoptosis of pre‐existing osteoblasts covering active bone surfaces. Moreover, our findings
showing that increased osteoblast apoptosis and reduction in serum osteocalcin observed …

[HTML][HTML] Osteoblast-induced osteoclast apoptosis by fas ligand/FAS pathway is required for maintenance of bone mass

L Wang, S Liu, Y Zhao, D Liu, Y Liu, C Chen… - Cell Death & …, 2015 - nature.com
… significant bone loss in … osteoblast-induced osteoclast apoptosis via FASL/FAS signaling
is a previously unrecognized mechanism that has an important role in the maintenance of bone