Dual-responsive nanoparticles targeting bone microenvironment for synergistic chemoimmunotherapy of osteosarcoma by remodeling immune microenvironment
J Li, S Liao, Y Wu, J Bi, Y Han, Y Zhang, M Xu, W Bi - Nano Today, 2023 - Elsevier
Low delivery efficiency of chemotherapy drugs, poor immunogenicity and suppressive immune
microenvironment of tumors seriously affect the prognosis of osteosarcoma (OS) patients. …
microenvironment of tumors seriously affect the prognosis of osteosarcoma (OS) patients. …
Augmenting the synergies of chemotherapy and immunotherapy through drug delivery
… exert synergistic chemoimmunotherapy … chemoimmunotherapy is the tumor. This
strategy allows tumor cell killing via cytotoxicity and modulation of the tumor immune-microenvironment. …
strategy allows tumor cell killing via cytotoxicity and modulation of the tumor immune-microenvironment. …
Emerging strategies in cancer therapy combining chemotherapy with immunotherapy
Q Luo, L Zhang, C Luo, M Jiang - Cancer Letters, 2019 - Elsevier
… strategies and synergistic effects in response to chemo-immunotherapy are highlighted. We
… microenvironment barriers [73]. As a result, the co-delivery of chemo-immunotherapy offers a …
… microenvironment barriers [73]. As a result, the co-delivery of chemo-immunotherapy offers a …
Synergistic Chemoimmunotherapy Augmentation via Sequential Nanocomposite Hydrogel‐Mediated Reprogramming of Cancer‐Associated Fibroblasts in …
… a diverse array of immune cells to infiltrate the tumor microenvironment (TME)[5]. However,
it is … only slight wrinkles in the bone cortex, with osteolytic bone destruction and heterotopic …
it is … only slight wrinkles in the bone cortex, with osteolytic bone destruction and heterotopic …
Triple‐Combination Immunogenic Nanovesicles Reshape the Tumor Microenvironment to Potentiate Chemo‐Immunotherapy in Preclinical Cancer Models
X Shi, L Shu, M Wang, J Yao, Q Yao, S Bian… - Advanced …, 2023 - Wiley Online Library
… Here, a combination chemoimmunotherapeutic nanosystem … drug delivery in vivo and
synergistic antitumor efficacy via … to generate a chemoimmunotherapeutic effect in treating ICB‐…
synergistic antitumor efficacy via … to generate a chemoimmunotherapeutic effect in treating ICB‐…
Multifunctional 3D-printed scaffolds eradiate orthotopic osteosarcoma and promote osteogenesis via microwave thermo-chemotherapy combined with immunotherapy
L Ma, J Zhou, Q Wu, G Luo, M Zhao, G Zhong, Y Zheng… - Biomaterials, 2023 - Elsevier
… may effectively inhibit tumor recurrence through synergistic immunotherapy. During long-term …
titanium scaffolds provide a structural microenvironment for bone regeneration. This study …
titanium scaffolds provide a structural microenvironment for bone regeneration. This study …
[HTML][HTML] Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer therapy: recent advances and perspectives
… Chemoimmunotherapy (CIT) as a promising approach in both for the first-line and relapsed
… of their participation and role of potential synergies in CIT approach is determinant. In this …
… of their participation and role of potential synergies in CIT approach is determinant. In this …
[HTML][HTML] Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
J Qi, F Jin, Y You, Y Du, D Liu, X Xu, J Wang… - Nature …, 2021 - nature.com
… In conclusion, this study presents a strategy to increase the tumor accumulation of drugs
by hitchhiking with leukocytes, and the synergistic strategy of chemo-immunotherapy not only …
by hitchhiking with leukocytes, and the synergistic strategy of chemo-immunotherapy not only …
[HTML][HTML] Hypoxia engineered bone marrow mesenchymal stem cells targeting system with tumor microenvironment regulation for enhanced chemotherapy of breast …
J Zu, L Tan, L Yang, Q Wang, J Qin, J Peng, H Jiang… - Biomedicines, 2021 - mdpi.com
… However, the regulation of the tumor microenvironment could further inhibit the growth of
tumors. In this study, we introduced a system consisting of hypoxia-engineered bone marrow …
tumors. In this study, we introduced a system consisting of hypoxia-engineered bone marrow …
Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone …
X Mu, M Zhang, A Wei, F Yin, Y Wang, K Hu, J Jiang - Nanoscale, 2021 - pubs.rsc.org
… in synergistic chemoimmunotherapy for PCa bone metastases. … nanoparticles for PCa bone
metastasis treatment. … of the immunosuppressive tumor microenvironment and inhibit the …
metastasis treatment. … of the immunosuppressive tumor microenvironment and inhibit the …