… bone growth by implanting Mg-based devices, the underlying mechanism of this effect is still
unclear. In order to safely use Mg-… rationale to study Mg ions on bone marrow stromal cells …

… influence of Mg 2+ ions on osteogenesis. Yoshiwaza et al. were among the few to investigate
the specific osteogenic pathways that are affected by magnesium. They found that Mg 2+ …

… Introducing magnesium ions into titanium implants is a second treatment strategy. In a
recent study, Okuzu et al25 introduced Mg2+ into titanium implants using the alkali and heat …

… Mg 2+ release, although this capability could have a marked impact in bone regeneration. …
both injectable scaffolds and Mg 2+ release system for bone regeneration. The biodegradable …

… The increased influx of magnesium ions significantly improved the release of neuronal …
Mg 2+ enhances bone regeneration by upregulating COL10A1 and VEGF expression in …

… regeneration of damaged tissues. For instance, the advanced combination of magnesium ions
(Mg 2+ ) and bone … , we utilized the coordination reaction of metal ion ligand to construct a …

… In this review, we focus on the role of these metal ions integrated in scaffolds for bone
regeneration and hope to contribute new inspiration and breakthroughs to inspire future research. …

… time of its formation, and can promote bone densification [16,17,18,19,20,21]. Magnesium
ion is the fourth most abundant ion in the body and 67% is stored in bones and teeth. Thus, …

… Mg 2+ at different stages of bone healing, we demonstrated that the bone regeneration rate
and the quality of newly formed bone tissues depend on the release profile of Mg 2+ 18,19 . …

… Although magnesium ions have been previously reported to promote bone regeneration,
the burst and excessive release of Mg 2+ may actually lead to bone loss [8], [9], [12], [13], [14]. …