… This review aims to summarize the deep link between blood vessels and bone formation
that occurs during bone regeneration when MSCs, their derivatives—extracellular vesicles (EVs…

… in the development of tissue-engineered bone; however, an active blood … angiogenesis
and osteogenesis are under evaluation and development to actively stimulate bone regeneration…

… of angiogenesis and osteogenesis during both skeletal development and postnatal bone …
on the molecular cross-talk between angiogenesis and osteogenesis. In particular, we will …

… have attracted attention in bone regeneration field. The vesicles … important roles of exosomes
in osteogenesis both in vitro and … to regulate osteogenesis and promote bone regeneration. …

… bone formation (osteomiRs) and/or angiogenesis (angiomiRs). However, as hypoxia is a major
driving force behind bone angiogenesis, … role in osteogenesis as well as angiogenesis to …

… dual functioning feature to enhance angiogenesis and osteogenesis simultaneously. In …
bone regeneration ie ‘cartilage formation as a median between angiogenesis and osteogenesis…

… angiogenic and osteogenic induction. As previously highlighted endogenous VEGF is important
for endochondral bone formation, … VEGF in normal bone formation and repair, treatment …

… In bone, vasculature is essential for cartilage resorption and angiogenesis temporally
precedes osteogenesis: the origin of bone is the artery carrying calcium and phosphate ions. …

… importance of vascularization during bone healing and remodeling, and … angiogenesis
and vasculogenesis at site of ischemic wounds. Distraction osteogenesis, a bone regeneration …

… and OP-1, with angiogenic and osteogenic activity confirms the importance of these two
processes in human skeletal healing. In this review, the role of osteogenic factors in the adaptive …