A comparative analysis of the osteogenic effects of BMP-2, FGF-2, and VEGFA in a calvarial defect model

B Behr, M Sorkin, M Lehnhardt, A Renda… - … Engineering Part A, 2012 - liebertpub.com
… The areas presented in Figure 3 show the dura mater and one bony edge of the defect. At …
what we have previously observed upon treatment of parietal defects with FGF-2, −9, and −18. …

Outcomes of regenerative treatment with rh PDGF‐BB and rh FGF2 for periodontal intra‐bony defects: a systematic review and meta‐analysis

V Khoshkam, HL Chan, GH Lin, J Mailoa… - Journal of Clinical …, 2015 - Wiley Online Library
… -BB and FGF-2 for treating periodontal defects in clinical trials, … growth factors for regenerating
periodontal intra-bony defects. … intra-bony defects were used and analysed for this review. …

Autologous bone grafts with MSCs or FGF-2 accelerate bone union in large bone defects

H Murakami, T Nakasa, M Ishikawa, N Adachi… - Journal of Orthopaedic …, 2016 - Springer
… uniting the fragments); 3, incomplete bony union (presence of a small amount of cartilage
in the callus); and 4, complete bony union. Histological evaluation of fracture healing was …

Efficacy of FGF2 in Periodontal Regeneration in a Case of Severe Intrabony Defect and Furcation Involvement With 15‐Month Follow‐Up

S Takayama, S Murakami - Clinical Advances in Periodontics, 2021 - Wiley Online Library
… Since we needed to treat plural bony defects at the same time, we chose FGF-2 treatment
in this case. The patient was informed and agreed on this procedure and signed the consent …

The potential of FGF-2 in craniofacial bone tissue engineering: A review

A Novais, E Chatzopoulou, C Chaussain, C Gorin - Cells, 2021 - mdpi.com
… for the treatment of deep intrabony periodontal defects demonstrated a clinical benefit of
FGF-2 in terms of bone fill [199]. A more recent meta-analysis of six randomized controlled trials …

Human intrabony defect regeneration with rh FGF2 and hyaluronic acid–a randomized controlled clinical trial

RB de Santana… - Journal of clinical …, 2015 - Wiley Online Library
… -enamel junction and crest of the defect and the intra-bony defect depth (INTRA) was …
Moreover, the depth of the three, two and one-wall sub-components of the bony defect were …

Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice

LF Charles, JL Woodman, D Ueno, G Gronowicz… - Experimental …, 2015 - Elsevier
… In old mice, but not young, there was enhanced bony fill in the central bone defect area
when the BMP-2 was supplemented with FGF-2. Histological analysis of the center of the defect

A randomized clinical trial evaluating rh-FGF-2/β-TCP in periodontal defects

DL Cochran, TJ Oh, MP Mills, DS Clem… - Journal of Dental …, 2016 - journals.sagepub.com
… The patient also had to have a tooth (target) with a pocket depth ≥7 mm with a ≥4-mm
infrabony defect and at least 1 bony wall. Sufficient keratinized tissue for complete tissue …

Long-term observation of regenerated periodontium induced by FGF-2 in the beagle dog 2-wall periodontal defect model

J Anzai, T Nagayasu-Tanaka, A Terashima, T Asano… - PLoS …, 2016 - journals.plos.org
… the defect bottom to the apical end of the gingival epithelium, and height and area of the newly
formed bone in the FGF-2defect model, the periodontal tissue regenerated by FGF-2 was …

Endogenous FGF2 levels impact FGF2/BMP‐2 growth factor delivery dosing in aged murine calvarial bone defects

LT Kuhn, T Peng, G Gronowicz… - Journal of Biomedical …, 2021 - Wiley Online Library
bony defect. We developed a growth factor delivery system in the form of a layered coating
made of biomimetic calcium phosphate and polyelectrolyte multilayers that can be applied to …