… Botulinum neurotoxins (BoNTs), a family of bacterial proteins produced by the anaerobic
bacterium Clostridium botulinum, are potent blockers of synaptic transmission in peripheral …

… botulinum neurotoxins, the causative agents of botulism, block the neurotransmitter release
by specifically cleaving one of the three SNARE proteins … them, botulinum neurotoxin type A (…

… Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and
… Guided by this knowledge, we design heterodimeric VHHs by connecting two neutralizing …

… Clostridial botulinum neurotoxins are the … Botulinum neurotoxins (BoNTs) are a group of
proteins produced by different strains of Clostridium botulinum, and are responsible for botulism …

… (8,9) Cytosolic BoNT/A LC cleaves SNAP-25 (synaptosomal-associated protein of 25-kDa),
a SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) protein …

… In this review, we summarize the current understanding of Botulinum neurotoxin (BoNT) …
BoNTs belong to a family of neurotoxins which are produced by various Clostridium botulinum …

… Introduction: Botulinum neurotoxins (BoNTs) are proteins responsible for the deadly paralytic
disease botulism. Extreme toxicity, ease of production and lack of antidotes against BoNT …

… Botulinum neurotoxins (… protein receptor (SNARE) proteins in neurons prevents the release
of neurotransmitters, thus resulting in the muscle paralysis that is characteristic of botulism. …

… for designing a molecule to enhance the efficiency of the inhibition against the neurotoxic …
BoNTs are 150 kDa proteins consisting of two chains linked through a disulfide bond. The …

… and seven serotypes of botulinum neurotoxin (BoNT/A–BoNT/G). Botulinum neurotoxin
serotype A is synthesized in Clostridium botulinum as a ~150,000 M r single chain protein (1,296 …