… Key Contribution: This review describes the experimental use of botulinum neurotoxins
as tools to block synaptic function in specific brain modules and dissect activity-dependent …

… Matthews D, Molenaers G, Motta F, Garcia Ruiz PJ, Wissel J: Recommendations for the
use of botulinum toxin type A in the management of cerebral palsy. Gait Posture 2000; 11:67–79. …

The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …

… in children with cerebral palsy increased the length of these muscles.132, 133 The
observations that BTX injection may delay tendon lengthening surgery in cerebral palsy are …

For more than three decades, Botulinum neurotoxin (BoNT) has been used to treat a variety
of clinical conditions such as spastic or dystonic disorders by inducing a temporary paralysis …

… on the physiological effects of the botulinum toxins have been … term botulinum toxin, otherwise
we will precise botulinum toxin complex (ie, BoNT plus ANTPs) in opposition to neurotoxin …

… can still be induced to release normal quanta of acetylcholine, although non-physiologic …
(CNS) is receptive to toxin, as shown by the toxin’s ability to bind brain synaptosomes.It is not …

… Botulinum neurotoxins (BoNTs) are highly potent toxins responsible for a severe disease,
called botulism. … The same gangliosides dominate in brain of mammals and birds. In the adult …

… It is also the natural target of botulinum neurotoxins (BoNTs) causing a selective blockade
of … The scope of this review is to describe the principal steps implicated in botulinum toxin …

Botulinum neurotoxins (BoNTs) are potent inhibitors of synaptic vesicle fusion and transmitter
release. The natural target of BoNTs is the peripheral neuromuscular junction (NMJ) where…