… botulinum neurotoxins and both peripheral and spinal glial cells, mainly Schwann cells, …
underlying the interaction between BoNTs and glial cells. A better understanding of these …

This study investigated the presence of cell membrane docking proteins synaptosomal‐associated
protein, 25 and 23 kD ( SNAP ‐25 and SNAP ‐23) in satellite glial cells ( SGC s) of rat …

… Botulinum neurotoxins (BoNTs) are highly potent toxins responsible for a severe disease,
called botulism. They are also efficient therapeutic tools with an increasing number of …

… Within the CNS, glial cells seem to play a crucial role in … glial cells are present: macroglia
(which include astroglia, oligodendrocytes and radial cells, including Bergmann and Müller cells…

… terminals, where again by truncating respective SNAREs, it would inhibit neurotransmitter
release, thereby preventing the activation of second order neurons and neighboring glial cells. …

… This is a strong indication that BoNT/A may be transcytosed from nociceptive fibers in spinal
cord and may enter into glial cells. The third important finding of the present study derives …

… This cytokine data in combination with our control experiments of treatment of glial cells with
BoNT/A suggests that while the microglia cells were not directly affected by the BoNT/A (T5/…

… The results of our data from primary glial cell cultures showed that BoNT/A diminishes
microglial SNAP-23 and astrocytic SNAP-23 and -25. We also revealed that minocycline does not …

… from nociceptive fibers in spinal cord to glial cells, confirming that astrocytes express protein
… , and transcytosis between neurons and glial spinal cells in the CNS. Axonal retrograde …

… of glia scarring and reaction, as revealed by morphometric analysis of astrocytes, revealing
hyperactive glial cells in … analysis showing reduction in glial cell size in both perilesioned and …