Inflammatory bowel disease: between genetics and microbiota

N Younis, R Zarif, R Mahfouz - Molecular biology reports, 2020 - Springer
… introduction of a genetic panel containing these main genes denoted by … microbiota in the
pathogenesis IBD, and its orchestrated interaction with the genetic component of the disease

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

F Imhann, AV Vila, MJ Bonder, J Fu, D Gevers… - Gut, 2018 - gut.bmj.com
… We show for the first time that genetic risk variants associated with IBD influence the gut
microbiota in healthy individuals. Roseburia spp are acetate-to-butyrate converters, and a …

[HTML][HTML] Inflammatory bowel disease: genetics, epigenetics, and pathogenesis

I Loddo, C Romano - Frontiers in immunology, 2015 - frontiersin.org
… Although etiology remains largely unknown, recent research has suggested that genetic
factors, environment, microbiota, and immune response are involved in the pathogenesis. …

The gut microbiota and inflammatory bowel diseases

J Miyoshi, EB Chang - Translational Research, 2017 - Elsevier
… , as we currently have no measures to correct genetic anomalies. Several microbiome-based
interventions have been studied in IBD, including prebiotics, probiotics, and postbiotics. …

New frontiers in genetics, gut microbiota, and immunity: a rosetta stone for the pathogenesis of inflammatory bowel disease

M Zhou, J He, Y Shen, C Zhang… - BioMed research …, 2017 - Wiley Online Library
… evidence has shown that inflammatory bowel disease (IBD) is … disease that is mainly
manipulated by a series of interactions between genetics, environmental factors, and gut microbiota, …

[HTML][HTML] Genetic effects on the commensal microbiota in inflammatory bowel disease patients

H Aschard, V Laville, ET Tchetgen, D Knights… - … genetics, 2019 - journals.plos.org
microbiota have been shown to be associated with inflammatory bowel disease (IBD), and
dozens of IBD genetic … , the role of the microbiota in the etiology of IBD in terms of host genetic

[HTML][HTML] The gut microbiota and inflammatory bowel disease

K Matsuoka, T Kanai - Seminars in immunopathology, 2015 - Springer
genetic status of NOD2 and ATG18L genes, which are two major CD susceptibility genes,
was associated with alteration of the gut microbiota [… is caused by genetic and environmental …

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

H Chu, A Khosravi, IP Kusumawardhani, AHK Kwon… - Science, 2016 - science.org
… interactions during host-microbiota symbiosis, we tested if genetic pathways linked to CD …
autophagy elongation complex; BMDCs deleted in these genes likewise do not induce IL-10 …

The genetics of inflammatory bowel disease

JH Cho, CT Weaver - Gastroenterology, 2007 - gastrojournal.org
genes have established the complex interrelationships that control the lifelong host response
to the intestinal microbiota and have identified a number of pathways that can lead to IBD. …

Gut microbiota and inflammatory bowel disease

L Chen, J Wang - WIREs Mechanisms of Disease, 2022 - Wiley Online Library
… The potential role of gut mycobiome in the pathogenesis of inflammatory bowel disease (IBD…
In IBD patients, genetic and/or environmental factors lead to dysbiosis of the gut microbiota, …